The socioeconomic effects of an iliofemoral venous thrombosis

O’Donnell, Thomas F.; Browse, N L; Burnand, K. G.; Thomas, M. Lea

doi:10.1016/0022-4804(77)90030-0

Cited by 267 publications

(94 citation statements)

References 13 publications

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“…The postphlebitic syndrome is a serious condition causing disability in those with end-stage disease (Immelman and Jeffery 1984). Most patients with proven symptomatic DVT will develop the syndrome 5-10 years after thrombosis (O'Donnell et al 1977, Browse et al 1980, Strandness et al 1983, Lindner et al 1986). These patients consume considerable resources from a wide range of health care providers (O'Donnell et al 1977, Skene et al 1992.…”

Section: Postphlebitic Syndrome After Hip Arthroplasty 43 Patients Fomentioning

confidence: 99%

Postphlebitic syndrome after hip arthroplasty: 43 patients followed at least 5 years

McNally¹,

McAlinden²,

O’Connell³

et al. 1994

Acta Orthopaedica Scandinavica

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Section: Postphlebitic Syndrome After Hip Arthroplasty 43 Patients Fomentioning

confidence: 99%

Postphlebitic syndrome after hip arthroplasty: 43 patients followed at least 5 years

McNally¹,

McAlinden²,

O’Connell³

et al. 1994

Acta Orthopaedica Scandinavica

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“…These more severe cases are associated with recurrent hospitalization, high health-care costs, and disability. 4,5 Venous insufficiency with trophic skin changes or ulceration is a frustrating problem, which many physicians approach with a sense of ennui. This may be due to the chronic and remitting nature of the problem, the need for lifestyle modification, inconvenient therapies, and contradictory information regarding medical and surgical management.…”

mentioning

confidence: 99%

Chronic Venous Insufficiency and Venous Ulceration

Alguire

Mathes

1997

J Gen Intern Med

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OBJECTIVE:To review and summarize the literature on the normal venous circulation of the leg, and the epidemiology, pathophysiology, and treatment of chronic venous insufficiency (CVI).DATA SOURCES: English-language articles identified through a MEDLINE search using the terms venous insufficiency or varicose ulcer and epidemiology, pathophysiology, diagnosis, and clinical trial (pt), and selected cross-references. STUDY SELECTION:Articles on epidemiology, pathophysiology, and treatment of CVI. Randomized, controlled studies were specifically sought for treatment efficacy. DATA EXTRACTION:Data were manually extracted from selected studies and reviews; emphasis was placed on information relevant to the general internist. pproximately 5 million people in the United States exhibit some evidence of chronic venous insufficiency (CVI) and between 400,000 and 500,000 of these individuals have or will develop a venous leg ulcer. 1-3 The signs of CVI include engorgement of the cutaneous veins and dependent edema in mildly affected patients to pigmentation, dermatitis, and ulceration in the more severe cases. Although most patients are asymptomatic, others have leg heaviness and aching or recurrent and recalcitrant leg ulcers punctuated by bouts of cellulitis. These more severe cases are associated with recurrent hospitalization, high health-care costs, and disability. 4,5 Venous insufficiency with trophic skin changes or ulceration is a frustrating problem, which many physicians approach with a sense of ennui. This may be due to the chronic and remitting nature of the problem, the need for lifestyle modification, inconvenient therapies, and contradictory information regarding medical and surgical management. Nevertheless, CVI, including ulceration, is a manageable problem. The purpose of this review is to present the normal anatomy and physiology of the venous circulation and to summarize the epidemiology, pathophysiology, and treatment of CVI. DATA SYNTHESIS: METHODSA MEDLINE search for relevant English-language articles published between 1966 and 1996 was completed using the following MeSH terms: venous insufficiency or varicose ulcer and epidemiology, pathophysiology, diagnosis, and clinical trial (pt). When selecting articles on treatment, randomized, controlled trials were reviewed whenever possible. Emphasis was placed on reviewing articles with clinical relevance for internal medicine physicians. ANATOMY AND NORMAL PHYSIOLOGYVenous blood from the skin and subcutaneous fat is collected in a system of superficial venules and veins that drain toward the deep venous system underneath the fascia via three major pathways: (1) through the long or short saphenous veins, which join the deep system at the saphenofemoral and saphenopopliteal junctions; (2) through the perforating veins originating from the long or short saphenous veins or their branches; or (3) directly into the deep venous system or bypass the deep system entirely and enter the pelvis. 6 Deep veins are categorized as either intramuscular or intermuscular; o...

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“…These data definitively demonstrate that in acute venous thrombosis the lymphatic system drain more interstitial fluid in order to reduce the local edema. The incidence of postthrombotic syndrome is nearly 35%-69% at three years after deep venous thrombosis and from 49% to 100% after five to ten years [28][29][30][31][32][33][34][35][36][37][38][39][40].…”

Section: Discussionmentioning

confidence: 99%

Investigation of the Leg Lymphatic Function in Patients with Leg Acute Venous Thrombosis and in Patients with Leg Post-Thrombotic Syndrome

Cariati¹

2012

TOCVJ

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Lymphatic and venous systems work together to drain interstitial fluid and blood respectively. Data on lymphatic function in chronic venous insufficiency and in chronic venous ulcerations are discordant. Modification of lymphatic function in acute venous thrombosis have been never described. The aim of this study is to report the modifications of the function of the lymphatic system in acute venous thrombosis, chronic venous ulceration and post-thrombotic syndrome. Discussion: The compensatory function of lymphatic system in acute venous thrombosis is definitively demonstrated. The lymphatic drainage of the limb affected by chronic venous ulceration is reduced. After the healing of the ulceration the lymphatic flow of the limbs affected by post-thrombotic syndrome improves but it remains under the levels of normal subjects.

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The socioeconomic effects of an iliofemoral venous thrombosis

Cited by 267 publications

References 13 publications

Postphlebitic syndrome after hip arthroplasty: 43 patients followed at least 5 years

Postphlebitic syndrome after hip arthroplasty: 43 patients followed at least 5 years

Chronic Venous Insufficiency and Venous Ulceration

Investigation of the Leg Lymphatic Function in Patients with Leg Acute Venous Thrombosis and in Patients with Leg Post-Thrombotic Syndrome

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