The Social Value Of Vaccination Programs: Beyond Cost-Effectiveness

Luyten, Jeroen; Beutels, Philippe

doi:10.1377/hlthaff.2015.1088

Cited by 69 publications

(50 citation statements)

References 50 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In addition to reducing preventable premature mortality, the practice of vaccination is cost‐effective, increasing parent or carer productivity, and lowering health care costs by reducing childhood morbidity (Ozawa 2012; WHO 2018). Childhood vaccination also has a broader social benefit of promoting health equity by ensuring the distribution of health within populations, and contributes to the public good by supporting disease containment (Luyten 2016). …”

Section: Introductionmentioning

confidence: 99%

Face-to-face interventions for informing or educating parents about early childhood vaccination

Kaufman

Ryan

Walsh

et al. 2018

Cochrane Database of Systematic Reviews

165

122

View full text Add to dashboard Cite

BackgroundEarly childhood vaccination is an essential global public health practice that saves two to three million lives each year, but many children do not receive all the recommended vaccines. To achieve and maintain appropriate coverage rates, vaccination programmes rely on people having sufficient awareness and acceptance of vaccines.Face‐to‐face information or educational interventions are widely used to help parents understand why vaccines are important; explain where, how and when to access services; and address hesitancy and concerns about vaccine safety or efficacy. Such interventions are interactive, and can be adapted to target particular populations or identified barriers.This is an update of a review originally published in 2013.ObjectivesTo assess the effects of face‐to‐face interventions for informing or educating parents about early childhood vaccination on vaccination status and parental knowledge, attitudes and intention to vaccinate.Search methodsWe searched the CENTRAL, MEDLINE, Embase, five other databases, and two trial registries (July and August 2017). We screened reference lists of relevant articles, and contacted authors of included studies and experts in the field. We had no language or date restrictions.Selection criteriaWe included randomised controlled trials (RCTs) and cluster‐RCTs evaluating the effects of face‐to‐face interventions delivered to parents or expectant parents to inform or educate them about early childhood vaccination, compared with control or with another face‐to‐face intervention. The World Health Organization recommends that children receive all early childhood vaccines, with the exception of human papillomavirus vaccine (HPV), which is delivered to adolescents.Data collection and analysisWe used standard methodological procedures expected by Cochrane. Two authors independently reviewed all search results, extracted data and assessed the risk of bias of included studies.Main resultsIn this update, we found four new studies, for a total of ten studies. We included seven RCTs and three cluster‐RCTs involving a total of 4527 participants, although we were unable to pool the data from one cluster‐RCT. Three of the ten studies were conducted in low‐ or middle‐ income countries.All included studies compared face‐to‐face interventions with control. Most studies evaluated the effectiveness of a single intervention session delivered to individual parents. The interventions were an even mix of short (ten minutes or less) and longer sessions (15 minutes to several hours).Overall, elements of the study designs put them at moderate to high risk of bias. All studies but one were at low risk of bias for sequence generation (i.e. used a random number sequence). For allocation concealment (i.e. the person randomising participants was unaware of the study group to which participant would be allocated), three were at high risk and one was judged at unclear risk of bias. Due to the educational nature of the intervention, blinding of participants and personnel was not possible in any ...

show abstract

Section: Introductionmentioning

confidence: 99%

Face-to-face interventions for informing or educating parents about early childhood vaccination

Kaufman

Ryan

Walsh

et al. 2018

Cochrane Database of Systematic Reviews

165

122

View full text Add to dashboard Cite

show abstract

“…It is estimated that childhood vaccines currently save 2–3 million lives annually and many more deaths could be averted with an elevated vaccination coverage [ 2 ]. Vaccinations can also minimize inappropriate use of antibiotics by reducing antibiotic use as a result of fewer infections among vaccinated individuals [ 3 , 4 ]. Vaccinations have been shown to have a significant positive effect on child growth by reducing stunting and children being underweight [ 5 ].…”

Section: Introductionmentioning

confidence: 99%

Understanding the Improvement in Full Childhood Vaccination Coverage in Ethiopia Using Oaxaca–Blinder Decomposition Analysis

et al. 2020

View full text Add to dashboard Cite

In Ethiopia, full vaccination coverage among children aged 12–23 months has improved in recent decades. This study aimed to investigate drivers of the improvement in the vaccination coverage. The Oaxaca–Blinder decomposition technique was applied to identify the drivers using data from Ethiopian Demographic and Health Survey conducted in 2000 and 2016. The vaccination coverage rose from 14.3% in 2000 to 38.5% in 2016. The decomposition analysis showed that most of the rise in vaccination coverage (73.7%) resulted from the change in the effect of explanatory variables over time and other unmeasured characteristics. Muslim religion had a counteracting effect on the observed increase in vaccination coverage. The remaining 26.3% of the increase was attributed to the change in the composition of the explanatory variables between 2000 and 2016, with maternal educational level and maternal health care utilization as significant contributors. The findings highlight the need for further improvements in maternal health care utilization and educational status to maintain the momentum towards universal coverage of childhood vaccination. Targeted intervention among Muslim-dominated communities is also needed to improve the current situation. Besides which, future studies need to be conducted to identify additional potential modifiable factors.

show abstract

“…Also screening and (non-)pharmaceutical intervention strategies have not been fully explored with IBMs for many diseases. Given the heterogeneous nature of bio-medical and socioeconomic data and the accelerating health care expenditures, IBMs become progressively useful to inform policy makers, particularly in combination with efficiency and equity analyses [ 106 , 107 ]. There are relatively few papers with an IBM for stochastic outbreak analysis under high vaccination coverage, for example for vaccine-preventable childhood diseases.…”

Section: Discussionmentioning

confidence: 99%

Lessons from a decade of individual-based models for infectious disease transmission: a systematic review (2006-2015)

et al. 2017

Self Cite

View full text Add to dashboard Cite

BackgroundIndividual-based models (IBMs) are useful to simulate events subject to stochasticity and/or heterogeneity, and have become well established to model the potential (re)emergence of pathogens (e.g., pandemic influenza, bioterrorism). Individual heterogeneity at the host and pathogen level is increasingly documented to influence transmission of endemic diseases and it is well understood that the final stages of elimination strategies for vaccine-preventable childhood diseases (e.g., polio, measles) are subject to stochasticity. Even so it appears IBMs for both these phenomena are not well established. We review a decade of IBM publications aiming to obtain insights in their advantages, pitfalls and rationale for use and to make recommendations facilitating knowledge transfer within and across disciplines.MethodsWe systematically identified publications in Web of Science and PubMed from 2006-2015 based on title/abstract/keywords screening (and full-text if necessary) to retrieve topics, modeling purposes and general specifications. We extracted detailed modeling features from papers on established vaccine-preventable childhood diseases based on full-text screening.ResultsWe identified 698 papers, which applied an IBM for infectious disease transmission, and listed these in a reference database, describing their general characteristics. The diversity of disease-topics and overall publication frequency have increased over time (38 to 115 annual publications from 2006 to 2015). The inclusion of intervention strategies (8 to 52) and economic consequences (1 to 20) are increasing, to the detriment of purely theoretical explorations. Unfortunately, terminology used to describe IBMs is inconsistent and ambiguous. We retrieved 24 studies on a vaccine-preventable childhood disease (covering 7 different diseases), with publication frequency increasing from the first such study published in 2008. IBMs have been useful to explore heterogeneous between- and within-host interactions, but combined applications are still sparse. The amount of missing information on model characteristics and study design is remarkable.ConclusionsIBMs are suited to combine heterogeneous within- and between-host interactions, which offers many opportunities, especially to analyze targeted interventions for endemic infections. We advocate the exchange of (open-source) platforms and stress the need for consistent “branding”. Using (existing) conventions and reporting protocols would stimulate cross-fertilization between research groups and fields, and ultimately policy making in decades to come.Electronic supplementary materialThe online version of this article (doi:10.1186/s12879-017-2699-8) contains supplementary material, which is available to authorized users.

show abstract

The Social Value Of Vaccination Programs: Beyond Cost-Effectiveness

Cited by 69 publications

References 50 publications

Face-to-face interventions for informing or educating parents about early childhood vaccination

Face-to-face interventions for informing or educating parents about early childhood vaccination

Understanding the Improvement in Full Childhood Vaccination Coverage in Ethiopia Using Oaxaca–Blinder Decomposition Analysis

Lessons from a decade of individual-based models for infectious disease transmission: a systematic review (2006-2015)

Contact Info

Product

Resources

About