The slippery road of adherence in chronically ill individuals

Studenic, Paul; Aletaha, Daniel

doi:10.1093/rheumatology/kez495

Cited by 2 publications

(2 citation statements)

References 13 publications

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“…However, patient's drug adherence was not considered in the study. There is a wide variability of drug adherence in patients, which strongly in uences clinical results (41). Previous treatment including b/tsDMARD administration at baseline did not in uenced on the time length.…”

Section: Discussionmentioning

confidence: 99%

The Impact of Time Length to Boolean Remission for Tight Disease Activity Control After Acquisition in Rheumatoid Arthritis Patients

Yoshii¹,

Chijiwa²,

Sawada

2021

Preprint

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Importance of time length to achieving clinical remission on disease activity control, daily activities (ADL) and quality of life (QOL) maintenance after the remission was investigated for patients with rheumatoid arthritis (RA).In patients who achieved remission once or more, relationship between time length from initiation to achieve remission (TL) and patients’ background data at baseline, and relationship between TL and mean simplified disease activity score (SDAI), modified Health Assessment Questionnaire Disability Index (HAQ-DI) score, pain score with visual analog scale (PS-VAS), Sharp/van der Heijde Score (SHS) and quality of life score (QOLS) at the first remission and thereafter were evaluated statistically. Patients were divided into two groups whether TL was within 6 months or longer (G≤6 and G>6). Change of the parameters and Boolean remission rate (BRR) after the first remission between the two groups were compared statistically.In 465 patients, TL correlated significantly with the SDAI score, the HAQ score, PS-VAS, SHS, and the QOLS after the remission. The SDAI score and the BRR after the first remission were significantly better in the G≤6 than in the G>6.TL is an important key to guarantee good disease activity control, ADL and QOL.

show abstract

Section: Discussionmentioning

confidence: 99%

The Impact of Time Length to Boolean Remission for Tight Disease Activity Control After Acquisition in Rheumatoid Arthritis Patients

Yoshii¹,

Chijiwa²,

Sawada

2021

Preprint

View full text Add to dashboard Cite

show abstract

“…However, the patient’s drug adherence was not considered in the study. There is a wide variability of drug adherence in patients, which strongly influences clinical results 41 . Previous treatment including b/tsDMARD administration at baseline did not influence on the time length.…”

Section: Discussionmentioning

confidence: 99%

The impact of time length to Boolean remission for tight disease activity control after acquisition in rheumatoid arthritis patients

Yoshii,

Chijiwa,

Sawada

2023

Sci Rep

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Clinical importance of time length from initiation under treat-to-target (T2T) strategy to acquisition of clinical remission (TL) in treating patients with rheumatoid arthritis (RA) on disease activity control, daily activities, and quality of life maintenance was investigated. In patients who achieved Boolean remission once or more, relationship between TL and patients’ background data at initiation, and relationship between TL and mean simplified disease activity score (SDAI), Health Assessment Questionnaire Disability Index (HAQ-DI) score, pain score with visual analog scale (PS-VAS), Sharp/van der Heijde Score (SHS) and quality of life score (QOLS) at the first remission and thereafter were evaluated statistically. Patients were divided into two groups whether TL was within 6 months or longer (G ≤ 6 and G > 6). Change of the parameters and Boolean remission rate (BRR) after the first remission between the two groups were compared statistically. In 465 patients, TL correlated significantly with the SDAI score, the HAQ score, PS-VAS, SHS, and the QOLS after the remission. The SDAI score and the BRR after the remission were significantly better in the G ≤ 6 than in the G > 6. TL is an important key to guarantee good and stable clinical course in treating under T2T.

show abstract

The slippery road of adherence in chronically ill individuals

Cited by 2 publications

References 13 publications

The Impact of Time Length to Boolean Remission for Tight Disease Activity Control After Acquisition in Rheumatoid Arthritis Patients

The Impact of Time Length to Boolean Remission for Tight Disease Activity Control After Acquisition in Rheumatoid Arthritis Patients

The impact of time length to Boolean remission for tight disease activity control after acquisition in rheumatoid arthritis patients

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