The Skin in Diagnosis of Alcoholism

Woeber, K

doi:10.1111/j.1749-6632.1975.tb19170.x

Cited by 12 publications

(4 citation statements)

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“…Alcoholic liver disease is commonly associated with cutaneous manifestations such as spider angiomas (whose number might correlate with the frequency of esophageal varices),[ 9 ] caput medusa, palmar erythema, icterus, pruritus, hyperpigmentation, urticaria, atrophic glossitis, parotid swelling, clubbing, watch glass deformity, and Terry's nails. [ 10 11 12 ] We had similar findings. However, there was a decreased incidence of features such as spider angiomas, palmar erythema, and Dupuytren's contracture (18%) compared to other studies in Caucasian population (72%), possibly due to darker skin type.…”

Section: Discussionsupporting

confidence: 74%

Cutaneous manifestations in disorders of hepatobiliary system

Godara

Thappa

Pottakkatt

et al. 2017

Indian Dermatol Online J

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Background:Hepatobiliary diseases are associated with various mucocutaneous changes that are directly and indirectly associated with these diseases. There is a dearth of studies from India dealing with cutaneous manifestations in liver disorders.Aim:This study was conducted to know the spectrum of cutaneous changes and their correlation with liver function tests in patients with disorders of hepatobiliary system.Methods:This was a descriptive study conducted among in patients and outpatients with primary hepatobiliary disorders at a tertiary care center in South India. Detailed history taking and examination was done. Visual analog score (VAS) and 5D itch score was employed to quantify pruritus. Correlation of liver function tests with pruritus and comparison of skin changes in the major disease groups was attempted.Results:A total of 303 patients were recruited. Hepatic mass/malignancy followed by nonalcoholic liver disease were the most common diagnoses. Icterus followed by pruritus were the most common cutaneous complaints. The mean VAS and 5D itch scores among the patients with pruritus were 4.7 ± 1.9 and 13.6 ± 4.9. The most common mucocutaneous findings observed were icterus (241 patients; 79.5%), ichthyosis/xerosis (172 patients; 56.7%), pallor (131 patients; 43.2%), excoriations (118 patients; 38.9%), hyperpigmented palmar creases (118 patients; 38.9%), clubbing (113 patients; 37.2%), and pedal edema (85 patients; 28%). There was statistically significant correlation between serum bilirubin levels and pruritus.Conclusion:The common mucocutaneous manifestations associated with primary hepatobiliary disorders were icterus, ichthyosis/xerosis, pallor, excoriations, hyperpigmented palmar creases, clubbing, and pedal edema.

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Section: Discussionsupporting

confidence: 74%

Cutaneous manifestations in disorders of hepatobiliary system

Godara

Thappa

Pottakkatt

et al. 2017

Indian Dermatol Online J

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“…These were similar to other studies where these symptoms were more commonly associated in patients of alcoholic liver disease. 8,9,10 Spider angiomas when present are an indication of increased risk of esophageal varices in patients of alcoholic liver disease and palmar erythema result from increased vasodilation due to androgen imbalance. 11 Also dupuytren's contracture when present is a strong pointer towards alcohol related liver damage.…”

Section: Discussionmentioning

confidence: 99%

Spectrum of Mucocutaneous Manifestations among Patients with Various Liver Disorders

Abrol¹,

Sharma²

2019

IJCMR

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Introduction:Skin is the first barrier against any external agent and a reflection of any deviation in the internal milieu. Any systemic disorder or organ dysfunction can leave its imprints on the skin and so also the liver certainly has cutaneous manifestations in case of any disorder affecting it. Study objective was to investigate the spectrum of cutaneous manifestations of various liver disorders and liver disease specific association. Material and methods:A total of 220 patients with primary liver disorders were taken up for the study after proper ethical clearance. A detailed clinical history was taken from the patients regarding liver disorder and cutaneous symptoms. A thorough clinical examination was done and all specific and nonspecific cutaneous manifestations were recorded. Results:Out of 220 patients, 135(61.3%) were males and 85(38.6%) were females with a male preponderance. Among the various liver disorders, most commonly seen was alcoholic liver disease seen in 84(38%) patients, nonalcoholic fatty liver disease (NAFLD) and nonalcoholic steatohepatitis(NASH) in 51(23.2%) patients, cirrhosis in 35(16%) patients. The most common cutaneous manifestation seen was icterus in 190(86.3%) patients, pruritus in 178(80.9%) patients, xerosis in 112(51%) patients. Conclusion:The knowledge of the cutaneous manifestations in liver disorders can be of great help as many liver disorders can easily be detected at their incipient stage. This study was done to assess the spectrum of cutaneous manifestations in liver disorders and a significant observation made was liver disease wise specific evaluation of cutaneous manifestations thus providing better insight into the type of liver diseases.

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“…They are recognized as such in common textbooks of internal medicine 6 , hepatology 7,8 , and dermatology 4 , as well as in clinical practice, and even by barmaids in order to diagnose liver cirrhosis in a customer 9 . However, disagreements between textbooks recommendations and actual literature are not uncommon 1,2 .…”

Section: Introductionmentioning

confidence: 99%

Precisión diagnóstica de las arañas vasculares para detectar enfermedad hepática en alcohólicos

2014

Gal. Clin.

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Introduction: Spider naevi are traditionally considered a sign of liver cirrhosis, particularly in patients with alcoholism. However, systematic evaluation of their diagnostic value in alcoholic patients has been scarcely performed. The aim of this study was to determine the diagnostic accuracy of the presence of spider neavi for liver disease detection in alcoholics using percutaneous liver biopsy as the reference standard.

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The Skin in Diagnosis of Alcoholism

Cited by 12 publications

References 0 publications

Cutaneous manifestations in disorders of hepatobiliary system

Cutaneous manifestations in disorders of hepatobiliary system

Spectrum of Mucocutaneous Manifestations among Patients with Various Liver Disorders

Precisión diagnóstica de las arañas vasculares para detectar enfermedad hepática en alcohólicos

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