Abstract:Abstract-Coumarins are oxygen-containing heterocyclic compounds, which is an important type of compounds in the discovery of bioactive molecules. Some work on the synthesis of bioactive coumarins has been done by other groups. Meanwhile, many synthetic methodologies have been put forward to construct skeleton of coumarins. Results: herein, typical methods constructing coumarin and its derivatives along with multifarious biological activity compounds in vitro and in vivo are summarized, which is of value for de… Show more
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