The Six Item Cognitive Impairment Test (6-CIT) as a Screening Test for Dementia: Comparison with Mini-Mental State Examination (MMSE)

Six-item cognitive impairment test (6CIT): pragmatic diagnostic accuracy study for dementia and MCI

“…Effect size (Cohen's d) calculations suggested a consistent difference in 6CIT scores between individuals with dementia and without dementia, but less consistency between MCI and without dementia non-MCI patients; effect sizes were comparable to those of other frequently used CSIs examined in this setting (Larner, 2014b). 6CIT and MMSE scores were highly (negatively) correlated (−0.73), as in previous reports: −0.91 (Brooke and Bullock, 1999), and −0.82 (both Upadhyaya et al, 2010 andTuijl et al, 2012). Compared to MMSE, 6CIT had better sensitivity for diagnosis of both dementia and MCI, as reflected also in weighted comparisons, although these measures are dependent on the exact MMSE cutoff chosen, and different methods for cutoff selection may give different results (Larner, 2015).…”

“…Although recommended as a dementia screening test in primary care (Brodaty et al, 2006), 6CIT has also been assessed in secondary care settings (Upadhyaya et al, 2010;Tuijl et al, 2012), as well as in this study. Access to detailed neuropsychological testing is far from universal in secondary care settings, and hence brief cognitive screening tests may contribute to patient assessment in this setting, as well as in primary care, if test metrics are satisfactory.…”

Effects of a Tailored Positive Psychology Intervention on Well-Being and Pain in Individuals With Chronic Pain and a Physical Disability

“…Exclusion criteria were as follows: currently participating in any psychosocial treatment (eg, psychotherapy, self-hypnosis training, biofeedback) once or more in the past month, reporting a history of hospitalization for psychiatric reasons within the past year, and having severe cognitive impairment defined as Z1 errors on the Six-Item Cognitive Impairment Test. 56 Eligible participants who provided consent received a link with access to the online baseline questionnaire. Participants who completed the baseline questionnaire online were then randomized to either the intervention group or the active control group using a computerized random number algorithm generated by the first author using Excel with a 1:1 allocation and blocks of 4 stratified by sex and disability diagnosis (ie, SCI, MS, NMD, and PPS).…”

Lower Cognitive Function in Older Patients with Lower Muscle Strength and Muscle Mass

“…The 6-CIT is a validated questionnaire in an older emergency department population [18] and is based on the 26-item Blessed Information-Memory-Concentration Scale [19]. The score on the 6-CIT ranges from 0 to 28 and has been used as a continuous and dichotomous measure with a proposed cutoff value of ≥10 points indicating low cognitive functioning [20].…”