The sinus lift with phycogenic bone substitute

Šimůneḱ, A.; Cierny, M; Kopecka, Dana; Kohout, A; Bukač, Josef; Vahalova, Dagmar

doi:10.1111/j.1600-0501.2005.01097.x

Cited by 25 publications

(33 citation statements)

References 18 publications

(25 reference statements)

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“…Biopsy specimens were harvested and dental implants were placed after a 9-month healing period in the present study. This healing period was chosen because it was the time point used in previously reported maxillary sinus and alveolar augmentation studies [33]. Cellular differentiation, augmentation material breakdown, and bony replacement were noted to be evident at the grafted sites largely preserving the dimensions of the alveolar ridge after 9 months of healing [33].…”

Section: Discussionmentioning

confidence: 99%

Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation

et al. 2011

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The aim of this study was to investigate the healing of human extraction sockets filled with β-tricalcium phosphate and type I collagen (β-TCP/Clg) cones with or without a barrier membrane. Twenty patients were divided in two groups: (A) β-TCP/Clg non-membrane and (B) β-TCP/Clg + barrier membrane. Clinical examination and biopsies from the grafted sites were collected 9 months later. Bone samples were analyzed using histomorphometry and immunohistochemistry. The horizontal dimension of the alveolar ridge was significantly reduced 9 months after socket preservation in the non-membrane group. There was bone formation with no significant differences between the two groups in the areas occupied by new bone (A = 42.4%; B = 45.3%), marrow (A = 42.7%; B = 35.7%), or residual graft (A = 9.7%; B = 12.5%). Immunohistochemistry revealed osteonectin expression in both groups. Both groups demonstrated sufficient amounts of vital bone and socket morphology to support dental implant placement after the 9-month healing period. A future trial to evaluate the alveolar outcomes at an earlier 6-month time point rather than the 9 months used in this study would be of interest.

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Section: Discussionmentioning

confidence: 99%

Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation

et al. 2011

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“…[17] In this study, we observed that after 6 months 43% of Algipore is still present, once again in line with the results obtained by Schopper after 7 months (33% ± 7.8%) and by Scarano et al after 6 months (37.1% ± 3.8%). [17] We know, from the previous study of Simunek et al [33] that Algipore is gradually resorbed and replaced by newly formed bone. During the time period of 6-15 months, the percentage of newly formed bone grows linearly, and the percentage of Algipore decreases linearly.…”

Section: S E V E R a L S T U D I E S R E P O R T E D T H E U S I N G mentioning

confidence: 99%

“…Porous biomaterials, such as Algipore, act as a scaffold for tissue regeneration. [15,17,33,35] They guide cell and vessels migration into the pores. Cell and vessel movement inside the pores are related to the degree of interconnection of the pores and to its size.…”

Section: S E V E R a L S T U D I E S R E P O R T E D T H E U S I N G mentioning

confidence: 99%

“…[31] On the other hand, the general properties of the phytogenic bone substitutes Algipore have been researched by a number of authors. [15,17,32,33] Algipore has been found to be a biocompatible, osteoconductive and resorbable biomaterial. [34] Histological evaluation has shown that a tight contact between newly formed bone and biomaterial particles, without gaps or interposition of connective fi brous tissue was present.…”

Section: S E V E R a L S T U D I E S R E P O R T E D T H E U S I N G mentioning

confidence: 99%

“…Cell and vessel movement inside the pores are related to the degree of interconnection of the pores and to its size. [15,17,33,35] The degree of interconnection of the pores in Algipore, as well as the pore size, modulate cellular ingrowth in the material, allowing osteoconduction. [36] Scarano et al [17,32] recently found that mineralized bone was present inside a large portion of the Algipore particles, which have a mean pore diameter of about 10 μm.…”

Section: S E V E R a L S T U D I E S R E P O R T E D T H E U S I N G mentioning

confidence: 99%

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Maxillary sinus floor augmentation with vegetal hydroxyapatite "versus" demineralized bovine bone: A randomized clinical study with a split-mouth design

et al. 2014

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Purpose: The objective of this paper was to compare histologically and histomorphometrically a hydroxyapatite originated by algae (Algipore) versus demineralized bovine bone (Bio-Oss Geistlich Pharma, Wolhusen, Switzerland) utilised as bone substitutes in maxillary sinus floor elevation with a split-mouth design. Materials and Methods: Five healthy patients underwent a bilateral maxillary sinus floor elevation procedure under local anesthesia. In each case, residual posterior maxillary bone height was between 2 mm and 5 mm. The original bone was augmented with a split-mouth design with 100% Algipore on the test side and 100% Bio-Oss on the contralateral control side. After a healing period of 6-8 months during the re-opening surgery biopsies were retrieved and Xive Implants (Dentsply Implants, Mannheim, Germany) were placed. Results: At microscopic level both Bio-Oss and Algipore blocks resulted well osseointegrated, without inflammatory infiltrate, with an high level of mineralization, without gap between the bone and biomaterial interfaces that resulted indistinguishable. A close contact between the two faces was observed without the presence of slits. Histomorphometrical analysis showed that, on average, the percentage of medullary space was higher for the Bio-Oss compared with Algipore (38.61% ±8.90% vs. 29.23% ±7.89%). In contrast, the mean value of residual particles of biomaterials was higher in Algipore than in Bio-Oss specimens (42.86% ±18.61% vs. 22.30% ±6.40% respectively). Conclusions: The data confirmed that sinus lift carried out with Algipore performed in a similar way of that carried out with Bio-Oss and that this material is safe, predictable and without invasiveness.

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Chemistry, ultrastructure and porosity of monophasic and biphasic bone forming materials derived from marine algae

Spassova¹,

Gintenreiter²,

Halwax

et al. 2007

Materialwissenschaft Werkst

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The research on bioceramics during the last decades has proved that the bioactivity of inorganic bone grafts depends fundamentally on an optimal combination of chemistry and structural porosity. This study presents a comparison of a resorbable monophasic hydroxyapatite (HA) and several newly developed resorbable biphasic hydroxyapatite -ß-tricalcium phosphate (HA/TCP) composites both derived from naturally grown red marine algae with respect to the phase composition, microstructure and porosity. The highly porous three dimensional mineral scaffold of the native alga is maintained in the final products all investigated materials and possesses a pronounced interconnecting microporous structure. There are generally high values of specific porosity calculated for all tested materials: 1.07 cm 3 /g for pure phycogenic HA and between 0.65 cm 3 /g and 1.04 cm 3 /g for phycogenic biphasic HA/TCP composites with various HA/TCP ratios. The ultrastructure of the phycogenic HA/TCP composites changes significantly with the building and the increase of the ß-TCP phase due to the bigger polyedric ß-TCP crystals compared to the finer polycrystalline HA. Despite these structural changes the interconnected porous scaffold is kept throughout the production process. In all investigated materials the porosity is mainly based on pores with pore sizes between 1 and 10 lm in diameter, which is given by the structure of the natural alga. The specific chemistry combined with the structural porosity is decisive for the high in-vivo bioactivity of the studied materials.Keywords: bone forming material, calcium phosphates, porosity, microstructure, chemistry Die Forschung an biokeramischen Materialien während der letzten Jahrzehnte hat ergeben, dass die Bioaktivität anorganischer Knochenersatzmaterialien grundsätzlich auf einer optimalen Kombination chemischer Parameter und Porosität basiert. Die vorliegende Studie präsentiert einen Vergleich zwischen einem monophasischen resorbierbaren Hydroxylapatit (HA) und mehreren neu entwickelten resorbierbaren biphasischen Hydroxylapatit -ß-Trikalziumphosphat (HA/TCP) Materialien, die aus natürlich gewachsenen Rotalgen gewonnen wurden, bezüglich Phasenzusammensetzung, Mikrostruktur und Porosität. Das dreidimensionale mineralische Stützgewebe der natürlichen Alge besitzt eine ausgeprägt interkonnektierende Mikroporosität und wird bis zu den Endprodukten aller untersuchten Materialien beibehalten. Die durchgeführten Analysen zeigen generell hohe Werte im Hinblick auf die spezifische Porosität: reiner phykogener HA 1.07 cm 3 /g sowie die phycogenen biphasischen HA/TCP Materialien mit unterschiedlichen HA/ TCP Verhältnissen zwischen 0.65 cm 3 /g und 1.04 cm 3 /g. Die Ultrastruktur der phykogenen biphasischen HA/TCP Materialien ändert sich signifikant mit der Bildung und der Konzentrationssteigerung der ß-TCP Phase auf Grund der größeren polyedrischen ß-TCP Kristalle im Vergleich zu dem feinen polykristallinen HA. Trotz dieser strukturellen Ä nderungen bleibt die interkonnektierend poröse Stützstruktur währ...

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The sinus lift with phycogenic bone substitute

Abstract: Sinus lift carried out with phycogenic bone substitute was shown to be an effective method with limited invasiveness and a high survival rate of implants (97.8%).

Cited by 25 publications

References 18 publications

Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation

Beta-tricalcium phosphate/type I collagen cones with or without a barrier membrane in human extraction socket healing: clinical, histologic, histomorphometric, and immunohistochemical evaluation

Maxillary sinus floor augmentation with vegetal hydroxyapatite "versus" demineralized bovine bone: A randomized clinical study with a split-mouth design

Chemistry, ultrastructure and porosity of monophasic and biphasic bone forming materials derived from marine algae

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