2024
DOI: 10.1093/glycob/cwae024
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The significant role of glycosaminoglycans in tooth development

Toshihiro Inubushi,
Priyanka Nag,
Jun-Ichi Sasaki
et al.

Abstract: This review delves into the roles of glycosaminoglycans (GAGs), integral components of proteoglycans, in tooth development. Proteoglycans consist of a core protein linked to GAG chains, comprised of repeating disaccharide units. GAGs are classified into several types, such as hyaluronic acid, heparan sulfate, chondroitin sulfate, dermatan sulfate, and keratan sulfate. Functioning as critical macromolecular components within the dental basement membrane, these GAGs facilitate cell adhesion and aggregation, and … Show more

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