2008
DOI: 10.1016/s1359-6349(08)70715-8
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The significance of the Van Nuys Prognostic Index in the management of ductal carcinoma in situ

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Cited by 19 publications
(24 citation statements)
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“…In reviewing this literature I strongly recommend starting with the materials and methods to determine whether the study utilized comparable methods to define the prognostic factors. Several recent studies incorporating prognostic factors for stratification of risk have demonstrated low risk subsets to a degree comparable to the published results of the VNPI (13–18). In this issue of the Journal, Altintas et al.…”
supporting
confidence: 71%
“…In reviewing this literature I strongly recommend starting with the materials and methods to determine whether the study utilized comparable methods to define the prognostic factors. Several recent studies incorporating prognostic factors for stratification of risk have demonstrated low risk subsets to a degree comparable to the published results of the VNPI (13–18). In this issue of the Journal, Altintas et al.…”
supporting
confidence: 71%
“…Many studies have demonstrated the utility of VNPI as a prognostic tool for DCIS [24][25][26] and the VNPI has been reflected in clinical practice recommendations for the management of DCIS. Thus, metabolic parameters can be recognized as a positive predictive factor of recurrent Breast Cancer disease and may identify a DCIS and DCIS-Mi population with good prognostic features.…”
Section: Discussionmentioning
confidence: 99%
“…An interesting risk stratification index to assess clinical management in DCIS has been defined by Van Nuys in 1997 and updated in 2003 by adding age as a fourth independent prognostic factor (11). This index has been used successfully by us and other investigators since 1997 (33–35). This is again confirmed in the current study since a statistical association was observed between a high VNPI score and a higher risk of recurrence (p = 0.049).…”
Section: Discussionmentioning
confidence: 99%