Abstract:Introduction: diffuse large B-cell lymphoma (DLBCL) represents the most common subtype of non-Hodgkin lymphomas (NHLs).Standard chemoimmunotherapy with rituximab, cyclophosphamide, doxorubicin, vincristine, prednisone (R-CHOP) is able to cure a significant proportion of patients; however, 30% of total cases experience relapse or have refractory disease. The international prognostic index (IPI) represents the most useful prognostic score, but it is exclusively based on clinical parameters. Previous studies show… Show more
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