The significance of neutrophilic extracleptal traps in the pathogenesis of hemocoagulation disorders in patients with colorectal cancer

Abstract

The article contains the main available data on the structures called neutrophil extracellular traps (NECs), the mechanisms of their formation and participation in pathophysiological processes are considered. Currently, scientific literature sources contain data on the structure of NVL and their role in the processes of antibacterial protection, thrombosis, as well as various neoplastic processes. However, there is no definite data regarding the exact role of NVL in the oncological process, and the duality of their influence in relation to tumor cells remains a matter of debate. In addition, data on the diagnostic significance of traps in clinical practice are also lacking.