The significance of low calcium and high potassium content in neoplastic tissue

A and B Antigens of Normal and Malignant Cells

“…Genic loss should produce an all-or-none effect which, as has been noted, does not occur. (Dunham, Nichols and Brunschwig, 1946;de Long, Coman, an. Zeidman, 1950), decreased adherence (McCutcheon, Coman and, Moore, 1948), absence of contact inhibition (Abercrombie andHeaysman, 1953, 1954) and accelerated electrophoretic mobility (Ambrose, James and Lowick, 1956) have all been demonstrated.…”

Interrelationships of Some Metabolic Effects of Testosterone Propionate in Normal Males During Restricted Sodium Intake 12

“…Relatively high ratios of water to nitrogen and of potassium to nitrogen occur in rapidly growing tissues such as the human fetus (31,32), regenerating rat liver (33)(34)(35),9 and certain neoplasms (35)(36)(37). It is possible that the high ratios of water to nitrogen and of potassium to ni- 9 Two studies describe separately a decrease in nitrogen (34) and an increase in potassium (35) per unit dry weight of regenerating rat liver.…”

“…It is possible that the high ratios of water to nitrogen and of potassium to ni- 9 Two studies describe separately a decrease in nitrogen (34) and an increase in potassium (35) per unit dry weight of regenerating rat liver. trogen retained during the first few days of T.P.…”

Ultrastructural changes of intercellular junctions in rat ascites hepatoma cells with calcium depletion

“…As is well known, the decreased mutual adhesiveness of cancer cells has been demonstrated by contrasting the mutual adhesiveness of normal epithelial and of cancer cells by means of micromanipulation (Coman, 1944;McCutcheon, Coman and Moore, 1948). As one of the conditions concerned with the decreased mutual adhesiveness, a decrease in Ca content in cancer tissue (Delong, Coman and Zeidman, 1950) and in epithelial cells after application of chemical carcinogen (Carruthers and Suntzeff, 1944) Preparation of cell suspension.-Cell suspension was prepared by the method previously described by Kudo et al (1974). The ascitic fluid (20 ml) was respectively withdrawn by i.p.…”