The significance and scope of evolutionary developmental biology: a vision for the 21st century

Moczek, Armin P.; Sears, Karen E.; Stollewerk, Angelika; Wittkopp, Patricia J.; Diggle, Pamela K.; Dworkin, Ian; Ledón‐Rettig, Cristina C.; Matus, David Q.; Roth, Siegfried; Abouheif, Ehab; Brown, Federico D.; Chiu, Chi Hua; Cohen, Sarah; Tomaso, Anthony W. De; Gilbert, Scott F.; Hall, Brian K.; Love, Alan C.; Lyons, Deirdre C.; Sanger, Thomas J.; Smith, Joel; Specht, Chelsea D.; Vallejo-Marin, Mario; Extavour, Cassandra G.

doi:10.1111/ede.12125

Cited by 98 publications

(95 citation statements)

References 325 publications

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“…Recent work has begun addressing these disciplines as an integrative discipline (Gilbert et al, 2015; Theis et al, 2016); however, they remain largely as separate conceptual entities. Since the hologenome concept was proposed nearly a decade ago, other multi-disciplinary fields, such as evolutionary developmental biology (Moczek et al, 2015), have recognized and, in a conceptual as well as empirical manner, addressed this challenge in two successive steps. The first of these emphasizes the value of applying hypotheses and/or mechanisms derived from laboratory studies to complementary experiments in nature (Gilbert, 2016), while the second tests evolutionary principles across different environments.…”

Section: Nature Of the Holobiontmentioning

confidence: 99%

The Hologenome Across Environments and the Implications of a Host-Associated Microbial Repertoire

Carrier

Reitzel

2017

Front. Microbiol.

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Our understanding of the diverse interactions between hosts and microbes has grown profoundly over the past two decades and, as a product, has revolutionized our knowledge of the life sciences. Through primarily laboratory experiments, the current framework for holobionts and their respective hologenomes aims to decipher the underpinnings and implications of symbioses between host and microbiome. However, the laboratory setting restricts the full spectrum of host-associated symbionts as compared to those found in nature; thus, limiting the potential for a holistic interpretation of the functional roles the microbiome plays in host biology. When holobionts are studied in nature, associated microbial communities vary considerably between conditions, resulting in more microbial associates as part of the “hologenome” across environments than in either environment alone. We review and synthesize empirical evidence suggesting that hosts may associate with a larger microbial network that, in part, corresponds to experiencing diverse environmental conditions. To conceptualize the interactions between host and microbiome in an ecological context, we suggest the “host-associated microbial repertoire,” which is the sum of microbial species a host may associate with over the course of its life-history under all encountered environmental circumstances. Furthermore, using examples from both terrestrial and marine ecosystems, we discuss how this concept may be used as a framework to compare the ability of the holobiont to acclimate and adapt to environmental variation, and propose three “signatures” of the concept.

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Section: Nature Of the Holobiontmentioning

confidence: 99%

The Hologenome Across Environments and the Implications of a Host-Associated Microbial Repertoire

Carrier

Reitzel

2017

Front. Microbiol.

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“…The problems of how and why forms change in evolution is still timely, and is one of the pillars of the young but maturing field evolutionary developmental biology (Moczek et al, 2015). In regard to evolution, specific forms that are more apt to perform particular functions should be favored, and increase in frequency over time.…”

Section: Introductionmentioning

confidence: 99%

Dissection of the complex genetic basis of craniofacial anomalies using haploid genetics and interspecies hybrids in Nasonia wasps

Werren

Cohen

Gadau

et al. 2016

Developmental Biology

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The animal head is a complex structure where numerous sensory, structural and alimentary structures are concentrated and integrated, and its ontogeny requires precise and delicate interactions among genes, cells, and tissues. Thus, it is perhaps unsurprising that craniofacial abnormalities are among the most common birth defects in people, or that these defects have a complex genetic basis involving interactions among multiple loci. Developmental processes that depend on such epistatic interactions become exponentially more difficult to study in diploid organisms as the number of genes involved increases. Here, we present hybrid haploid males of the wasp species pair Nasonia vitripennis and Nasonia giraulti, which have distinct male head morphologies, as a genetic model of craniofacial development that possesses the genetic advantages of haploidy, along with many powerful genomic tools. Viable, fertile hybrids can be made between the species, and quantitative trail loci related to shape differences have been identified. In addition, a subset of hybrid males show head abnormalities, including clefting at the midline and asymmetries. Crucially, epistatic interactions among multiple loci underlie several developmental differences and defects observed in the F2 hybrid males. Furthermore, we demonstrate an introgression of a chromosomal region from N. giraulti into N. vitripennis that shows an abnormality in relative eye size, which maps to a region containing a major QTL for this trait. Therefore, the genetic sources of head morphology can, in principle, be identified by positional cloning. Thus, Nasonia is well positioned to be a uniquely powerful model invertebrate system with which to probe both development and complex genetics of craniofacial patterning and defects.

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“…The emergence of the field of evolutionary developmental biology in the 1970s with the discovery of regulatory genes and emphasis on where, when, and to what degree these highly conserved genes are activated in different taxa, began to change previous attitudes (see ref. 18 for review). Some prominent evolutionary biologists still question the importance of developmental plasticity in evolutionary change (16), and some of its aspects remain controversial, but a number of its concepts are now well established in evolutionary thinking and practice (17).…”

Section: Phenotypic (Developmental) Plasticitymentioning

confidence: 99%

“…Some question whether EES additions and modifications, such as developmental plasticity and TEI, have been shown to have much evolutionary importance (14,16). An emerging body of literature is clarifying some of these issues (17)(18)(19).…”

mentioning

confidence: 99%

Assessing elements of an extended evolutionary synthesis for plant domestication and agricultural origin research

Piperno

2017

Proc. Natl. Acad. Sci. U.S.A.

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The development of agricultural societies, one of the most transformative events in human and ecological history, was made possible by plant and animal domestication. Plant domestication began 12,000–10,000 y ago in a number of major world areas, including the New World tropics, Southwest Asia, and China, during a period of profound global environmental perturbations as the Pleistocene epoch ended and transitioned into the Holocene. Domestication is at its heart an evolutionary process, and for many prehistorians evolutionary theory has been foundational in investigating agricultural origins. Similarly, geneticists working largely with modern crops and their living wild progenitors have documented some of the mechanisms that underwrote phenotypic transformations from wild to domesticated species. Ever-improving analytic methods for retrieval of empirical data from archaeological sites, together with advances in genetic, genomic, epigenetic, and experimental research on living crop plants and wild progenitors, suggest that three fields of study currently little applied to plant domestication processes may be necessary to understand these transformations across a range of species important in early prehistoric agriculture. These fields are phenotypic (developmental) plasticity, niche construction theory, and epigenetics with transgenerational epigenetic inheritance. All are central in a controversy about whether an Extended Evolutionary Synthesis is needed to reconceptualize how evolutionary change occurs. An exploration of their present and potential utility in domestication study shows that all three fields have considerable promise in elucidating important issues in plant domestication and in agricultural origin and dispersal research and should be increasingly applied to these issues.

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The significance and scope of evolutionary developmental biology: a vision for the 21st century

Cited by 98 publications

References 325 publications

The Hologenome Across Environments and the Implications of a Host-Associated Microbial Repertoire

The Hologenome Across Environments and the Implications of a Host-Associated Microbial Repertoire

Dissection of the complex genetic basis of craniofacial anomalies using haploid genetics and interspecies hybrids in Nasonia wasps

Assessing elements of an extended evolutionary synthesis for plant domestication and agricultural origin research

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