The shorter, the better

Mayerhofer, R.

doi:10.1002/latj.201190025

Cited by 3 publications

(1 citation statement)

References 3 publications

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“…Furthermore, the tissue ablation with ns laser sources depends on the linear absorption properties of the tissue and therefore on the color of the eye (1)(2)(3)(4)(5)(6)(7). However, such unintended results can be counteracted by using ultrashort pulses (USP) (8)(9)(10)(11)(12)(13). The main advantage of these pulseswhich have a pulse width of a few picoseconds or less-is to be near the regime of cold material ablation.…”

Section: Open Access Edited Bymentioning

confidence: 99%

Ophthalmic surgeries on post mortem porcine eyes with picosecond ultrashort laser pulses

Körber,

Fellinger,

Fritsche

et al. 2024

Front. Med.

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PurposeThis work demonstrates significant advantages in ophthalmic surgeries through the use of picosecond ultrashort laser pulses instead of state-of-the-art nanosecond laser pulses. These ultrashort lasers shall serve as universal tools more effectively combining advantages of high precision, low impact and economic advantages compared to existing instruments.MethodsAs samples, we used post-mortem porcine eyes on which we performed the experiments with both picosecond and nanosecond lasers. Performed surgeries were laser iridotomy, (post-) cataract treatment/capsulotomy and selective laser-trabeculoplasty. Pulse widths were between 12 ps and 220 ns with pulse energies between 30 μJ and 10 mJ at 532 nm and 1,064 nm. Additionally, we investigated accompanying shock waves, cavitation bubbles, and heat effects during the ablation processes.ResultsFor all surgeries, significant differences were observed between picosecond and nanosecond pulses: It was possible to scale the pulse energy down to 10 of microjoules rather than requiring millijoules, and resulting tissue ablations are much more precise, more deterministic and less frayed. The shock wave and cavitation bubble investigation revealed major differences in pressure between picosecond pulses (0.25 MPa, 50 μJ) and nanosecond pulses (37 MPa, 5 mJ). The heat input during ablation could be lowered by two orders of magnitude.ConclusionPicosecond ultrashort laser pulses show substantial benefits for several ophthalmic surgeries, with regard to ablation precision, shock wave generation and heat input. They are better than state-of-the-art ophthalmic nanosecond lasers in all aspects tested.

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Section: Open Access Edited Bymentioning

confidence: 99%

Ophthalmic surgeries on post mortem porcine eyes with picosecond ultrashort laser pulses

Körber,

Fellinger,

Fritsche

et al. 2024

Front. Med.

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Is it Cold Enough, Yet?

Mayerhofer¹,

May²,

Serbin³

2016

Laser Technik Journal

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Ultrashort‐pulse (USP) lasers have, since the late 1990s, been an exciting technology looking for opportunities to gain mass market application in industrial materials processing. In recent years, a wide range of new products offering innovative architectures and higher pulse energy combined with high pulsing frequencies are finding many uses in regular manufacturing, where they make components with unprecedented quality, accuracy and speed without visible signs of thermal interaction during the cutting or drilling process. Owing to the short duration of the pulses, the laser energy can be input to the material in a shorter time than heat can be transferred — leading to cutting and ablation without dross, burr or visible melt damage.

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