The Short-Term Antibacterial Activity of Three Selected Endodontic Sealers against Enterococcus faecalis Bacterial Culture

Rosa, M; Morozova, Yuliya; Moštěk, Roman; Holík, Pavel; Somolová, L; Novotná, B; Zábojníková, Soňa; Bogdanová, Kateřina; Langová, Kateřina; Voborná, Iva; Pospíšilová, Lenka; Kovařík, Josef

doi:10.3390/life12020158

Cited by 3 publications

(2 citation statements)

References 51 publications

(77 reference statements)

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“…Successful root canal treatment depends on the complete elimination of pathogenic bacteria [1]. Because antimicrobial activity plays an important role in the efficacy of endodontic irrigation used during root canal therapy, many studies have dealt with the antibacterial activity of endodontic irrigations [2,3]. Enterococcus faecalis has been repeatedly identified as one of the most resistant species in the oral cavity [4] and is the main microorganism associated with endodontic failure [5,6].…”

Section: Introductionmentioning

confidence: 99%

A Multi-Criteria Approach for Comparison of Ginger Extract and Conventional Irrigants in Root Canal Treatment

Abdollahi-Mansoorkhani¹,

Soleimani²,

Mahmoudi³

2022

Cureus

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BackgroundConsidering the importance of irrigation in dental root canal treatment, there is an urgent need to find a risk-free bioactive and antibacterial endodontic solution. Enterococcus faecalis, an anaerobic gram-positive coccus, has been identified as the main reason for endodontic infections. Several studies have been conducted on E. faecalis and periapical infection. Nowadays, plants used in traditional medicine play a role that is widely appreciated by researchers. One of these herbs is ginger which shows an acceptable antimicrobial effect on E. faecalis. Due to the highly crucial role that irrigation plays in the success of endodontic treatment, a comprehensive survey based on several criteria, namely, scientific, technical, and empirical, is required to address the goal of determining the best endodontic solution. MethodologyThe most important criteria are antibacterial activity, risks and hazards, cost, and availability. In this study, the analytical network process (ANP), which is a multi-criteria decision-making method, was applied to determine the best endodontic irrigant. ResultsSeveral alternatives were investigated using the ANP. In this study, 5.25% sodium hypochlorite (NaOCl) and 2% chlorhexidine were at the top of the list. According to the sensitivity analysis, 10% ethanolic ginger extract showed comparable results to 2.5% NaOCl. ConclusionsTo carefully prioritize endodontic irrigants a wide range of standards and criteria should be considered. Considering the low risk, great wettability, and active compounds of ginger extract, it can be a promising viable risk-free solution for root canal treatments.

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Section: Introductionmentioning

confidence: 99%

A Multi-Criteria Approach for Comparison of Ginger Extract and Conventional Irrigants in Root Canal Treatment

Abdollahi-Mansoorkhani¹,

Soleimani²,

Mahmoudi³

2022

Cureus

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“…This antibacterial capacity has been enhanced in vitro when using chitosan as a carrier; what may be attributed to the synergistic antimicrobial activity of chitosan and ZnO (Javed et al., 2020). In adjunctive endodontic treatments, silver and zinc have been tested when incorporated in nanocomposites (Jose et al., 2022), endodontic fillers (Al‐Quraine et al., 2023; Rosa et al., 2022) and irrigants (Ertem et al., 2017) either individually or in combinations.…”

Section: Resultsmentioning

confidence: 99%

Next‐generation antibacterial nanopolymers for treating oral chronic inflammatory diseases of bacterial origin

Toledano‐Osorio,

Osorio,

Bueno

et al. 2024

Int Endodontic J

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Background‘Periodontitis’ refers to periodontal destruction of connective tissue attachment and bone, in response to microorganisms forming subgingival biofilms on the root surface, while ‘apical periodontitis’ refers to periapical inflammatory processes occurring in response to microorganisms within the root canal system. The treatment of both diseases is based on the elimination of the bacterial challenge, though its predictability depends on the ability of disrupting these biofilms, what may need adjunctive antibacterial strategies, such as the next‐generation antibacterial strategies (NGAS). From all the newly developed NGAS, the use of polymeric nanotechnology may pose a potential effective approach. Although some of these strategies have only been tested in vitro and in preclinical in vivo models, their use holds a great potential, and therefore, it is relevant to understand their mechanism of action and evaluate their scientific evidence of efficacy.ObjectivesTo explore NGAS based on polymeric nanotechnology used for the potential treatment of periodontitis and apical periodontitis.MethodA systemic search of scientific publications of adjunctive antimicrobial strategies using nanopolymers to treat periodontal and periapical diseases was conducted using The National Library of Medicine (MEDLINE by PubMed), The Cochrane Oral Health Group Trials Register, EMBASE and Web of Science.ResultsDifferent polymeric nanoparticles, nanofibres and nanostructured hydrogels combined with antimicrobial substances have been identified in the periodontal literature, being the most commonly used nanopolymers of polycaprolactone, poly(lactic‐co‐glycolic acid) and chitosan. As antimicrobials, the most frequently used have been antibiotics, though other antimicrobial substances, such as metallic ions, peptides and naturally derived products, have also been added to the nanopolymers.ConclusionPolymeric nanomaterials containing antimicrobial compounds may be considered as a potential NGAS. Its relative efficacy, however, is not well understood since most of the existing evidence is derived from in vitro or preclinical in vivo studies.

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Evaluation of Antibacterial Effect of New Sealer “Neoseal” and Two Commercially Used Endodontic Sealers against Enterococcus faecalis: An In Vitro Study

Rayyan,

Sayed,

Reslan

et al. 2024

The Journal of Contemporary Dental Practice

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The Short-Term Antibacterial Activity of Three Selected Endodontic Sealers against Enterococcus faecalis Bacterial Culture

Cited by 3 publications

References 51 publications

A Multi-Criteria Approach for Comparison of Ginger Extract and Conventional Irrigants in Root Canal Treatment

A Multi-Criteria Approach for Comparison of Ginger Extract and Conventional Irrigants in Root Canal Treatment

Next‐generation antibacterial nanopolymers for treating oral chronic inflammatory diseases of bacterial origin

Evaluation of Antibacterial Effect of New Sealer “Neoseal” and Two Commercially Used Endodontic Sealers against Enterococcus faecalis: An In Vitro Study

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