The shape of the mitral annulus: A hypothesis of mechanical morphogenesis
Davide Ambrosi,
Luca Deorsola,
Stefano Turzi
et al.
Abstract:This paper investigates the role of mechanics in the morphogenesis of the annulus of the mitral valve. We represent the annulus in its embryonic stage as an elastic ring and we perform a mechanical simulation of the development process applying a distributed torque on the rod: because of the mechanical action of the other growing cardiac chambers on the atrio-ventricular region, it departs from a planar circular shape. The numerical integration of the mathematical rod model subject to a bending load yields a s… Show more
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