The shape of the aortic outflow velocity profile revisited: is there a relation between its asymmetry and ventricular function in coronary artery disease?

Abstract

Decreased myocardial function results in a more symmetrical outflow, while very asymmetrical traces suggest increased contractility, potentially inducing intra-cavity gradients during DSE. Therefore, including outflow symmetry as a clinical measurement provides additional information on patients with CAD.

Machine-learning–based exploration to identify remodeling patterns associated with death or heart-transplant in pediatric-dilated cardiomyopathy

“…In the normal LV, when contractility and loading are balanced, aortic outflow peaks around one third of the ejection period; and then gradually decreases, corresponding to decreased force development. When loading is disproportionally increased or contractility impaired, 17 force-development prolongs, resulting in late peaking outflow velocities with a rounded rather than triangular profile. Similarly, mitral Doppler patterns showed well-known changes associated with filling abnormalities, such as alterations in IVRT, E-wave peak and deceleration, A-wave contribution and heart-rate-related fusion, over and above absolute peak E and A values.…”

Image registration and atlas-based segmentation of cardiac outflow velocity profiles

“…This vector is calculated using the equivalent formula as in Equation 11 and denoted as e 3 . In this experiment the average error is µ(e 3 ) = 2.93% with standard deviation of σ(e 3 ) = 2.03%.…”

“…In everyday clinical practice, a detailed analysis of Doppler echocardiography in diagnostics and further patient management strategies [3,4]. Continuous wave Doppler outflow traces are mainly used to assess a potential pressure gradient across the aortic valve resulting from a narrowing of the valve.…”

“…The atlas-based segmentation of aortic blood velocity profiles proposed in this paper, is a prerequisite useful for the quantitative analysis of coronary artery disease and aortic stenosis, such as the one described in [8,3]. However, the motivation of this work is not only to solve the problem of the aortic outflow velocity profile registration, but also to present a more general approach for registration of other cardiac images such as mitral valve velocity profiles.…”