The severity of dissociative symptoms among patients with cannabis and synthetic cannabinoid use disorder: association with substance use characteristics and suicide

Yücens, Bengü; Kotan, Vahap Ozan; Okay, İhsan Tuncer; Göka, Erol

doi:10.1080/24750573.2018.1505451

Cited by 2 publications

(1 citation statement)

References 23 publications

(26 reference statements)

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“…Forty-four studies reported that early cannabis initiation was associated with psychotic outcomes, including earlier age of onset of psychosis ( 7 , 9 , 53 , 61 , 64 , 65 , 73 , 75 , 82 , 97 , 99 , 101 , 138 ), higher risks of psychotic symptoms ( 12 , 38 , 56 , 66 – 68 , 70 , 71 , 75 , 94 , 95 , 103 , 111 , 116 , 127 , 131 , 150 ) and greater severity of these symptoms ( 20 , 61 , 89 ), higher risks of psychosis ( 61 , 86 , 90 , 131 , 147 ), and higher risk of psychotic disorder ( 7 , 59 , 87 , 95 , 136 , 152 ) compared with later initiation or non-use of cannabis. Two studies ( 73 , 82 ) revealed that the onset of psychosis followed cannabis initiation on average 7–8 years after.…”

Section: Resultsmentioning

confidence: 99%

Variations of cannabis-related adverse mental health and addiction outcomes across adolescence and adulthood: A scoping review

Kaur

Bastien²,

Gagnon³

et al. 2022

Front. Psychiatry

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IntroductionEvidence supporting associations between cannabis use and many health outcomes is growing, however it remains unclear how such associations vary across the lifespan. We therefore aim to answer the following questions: (1) Are the risks of cannabis’s adverse effects on mental health and addiction-related outcomes different in adolescents than in adults? (2) What are the relationships between these cannabis’s adverse effects and (a) an individual’s age at first cannabis use, (b) age at assessment, and (c) duration of cannabis use?MethodsWe searched Medline, Embase, CINAHL, and PsychINFO from inception to 18 October 2021. Two reviewers independently screened studies and descriptively synthesized results.ResultsWe included 140 studies. Cannabis effects on mental health and addiction-related outcomes were worse in adolescents, early cannabis initiators and cannabis users who consumed for longest periods. Evidence of worse long-term adverse effects in adolescents was substantial for psychosis, cannabis, and nicotine use disorders; mixed for depression, suicidality, other substance use and disorders; and limited for anxiety. Additionally, acute cannabis exposure had the opposite trend with adults more often reporting adverse effects than adolescents.ConclusionThe available evidence suggests that cannabis use should be delayed as late as possible in adulthood and shortened in duration across the lifespan to decrease the risk of negative outcomes, while emphasizing the need for adapted harm reduction approaches. This scoping review provides evidence on the role of age and duration of exposure as determinants of cannabis-related adverse effects, which may inform prevention and harm reduction strategies.Systematic review registrationhttps://doi.org/10.17605/OSF.IO/BYG72

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Section: Resultsmentioning

confidence: 99%

Variations of cannabis-related adverse mental health and addiction outcomes across adolescence and adulthood: A scoping review

Kaur

Bastien²,

Gagnon³

et al. 2022

Front. Psychiatry

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Psychomotor performances relevant for driving under the combined effect of ethanol and synthetic cannabinoids: A systematic review

et al. 2023

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ObjectiveTo determine whether the acute co-consumption of ethanol and synthetic cannabinoids (SCs) increases the risk of a motor vehicle collision and affects the psychomotor performances relevant for driving.DesignSystematic review of the literature.Data sourcesElectronic searches were performed in two databases, unrestricted by year, with previously set method and criteria. Search, inclusion and data extraction were performed by two blind authors.ResultsTwenty articles were included, amounting to 31 cases of SCs-ethanol co-consumption. The impairment of psychomotor functions varied widely between studies, ranging from no reported disabilities to severe unconsciousness. Overall, a dose-effect relationship could not be observed.ConclusionDespite the biases and limitations of the literature studies, it seems likely that the co-consumption poses an increased risk for driving. The drugs might exert a synergistic effect on the central nervous system depression, as well as on aggressiveness and mood alterations. However, more research is needed on the topic.

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The severity of dissociative symptoms among patients with cannabis and synthetic cannabinoid use disorder: association with substance use characteristics and suicide

Cited by 2 publications

References 23 publications

Variations of cannabis-related adverse mental health and addiction outcomes across adolescence and adulthood: A scoping review

Variations of cannabis-related adverse mental health and addiction outcomes across adolescence and adulthood: A scoping review

Psychomotor performances relevant for driving under the combined effect of ethanol and synthetic cannabinoids: A systematic review

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