The severity of acute exacerbations of COPD and the effectiveness of pulmonary rehabilitation

Vitacca, Michele; Ambrosino, Nicolino; Belli, Stefano; Vigna, Matteo; Zampogna, Elisabetta; Aliani, Maria; Piaggi, Giancarlo; Paneroni, Mara

doi:10.1016/j.rmed.2021.106465

Cited by 5 publications

(1 citation statement)

References 27 publications

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“…Studies have also shown that training improved dyspnoea symptoms, muscular strength and activities of daily living in patients with chronic obstructive pulmonary disease (COPD) 12 13. Furthermore, pulmonary rehabilitation in patients after an acute exacerbation14 15 or in their stable phase of lung disease has been shown to be safe and effective 16 17. In terms of comorbidities, exercise could affect other body systems and functions, such as improving cardiovascular function,18 19 reducing mood disturbance,20 21 and improving skeletal muscle function 22 23…”

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confidence: 99%

Effects of full-body exercise-based pulmonary rehabilitation in patients with idiopathic pulmonary fibrosis: a systematic review and meta-analysis protocol

et al. 2022

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IntroductionIdiopathic pulmonary fibrosis (IPF) is a chronic lung disease characterised by progressive and irreversible fibrosis of the lung parenchyma, resulting in reduced lung function. Since conventional medicines can be associated with low effective rates and adverse events, pulmonary rehabilitation may be a promising non-pharmacological therapy for IPF. Thus, we aimed to evaluate the effects of full-body exercise-based pulmonary rehabilitation on patients with IPF by conducting a systematic review and meta-analysis of randomised controlled trials (RCTs).Methods and analysisThis systematic review and meta-analysis has been registered in the International Prospective Register of Systematic Reviews (PROSPERO). From inception to 31 August 2022, electronic databases in English and Chinese were searched, including PubMed, Embase, Web of Science, Cochrane Central Register of Controlled Trials among the English databases. China National Knowledge Infrastructure, Chinese Biomedical Literature, VIP Chinese Science and Technology Periodical, and Wan Fang Data were among the Chinese databases. Two independent reviewers then screened the potential RCT studies, which were analysed according to the Cochrane Handbook criteria. The efficacy and safety of full-body exercise pulmonary rehabilitation for IPF were evaluated based on outcomes, including exercise capacity measured by 6 min walking distance and quality of life measured by St. George’s Respiratory Questionnaire. Lung function was measured based on the forced vital capacity, total lung capacity, diffusing capacity of the lungs for carbon monoxide and dyspnoea assessed by the modified Medical Research Council scale.Ethics and disseminationEthical approval was not required for this systematic review and meta-analysis. Results will be published in a peer-reviewed journal and presented at conferences.PROSPERO registration numberCRD42021284293.

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