The Setting-Intervention Fit of Nine Evidence-Based Interventions for Substance Use Disorders Within HIV Service Organizations Across the United States: Results of a National Stakeholder-Engaged Real-Time Delphi Study

Garner, Bryan; Knudsen, Hannah K.; Zulkiewicz, Brittany; Tueller, Stephen; Gotham, Heather J.; Martin, Erika G.; Donohoe, Tom; Toro, Alyssa Katherine; Loyd, Katie; Gordon, Theodore J.

doi:10.1097/qai.0000000000002981

Cited by 4 publications

(4 citation statements)

References 40 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This specification helps researchers and practitioners have clarity about what the strategy versus intervention is. For example, within this special issue, Garner and colleagues [15] 2. Determining how much evidence is needed before an intervention can be adapted In a hybrid type II implementation-effectiveness study [16], Hamilton and colleagues originally proposed an adapted version of the evidence-based "Eban" intervention that had been tested and found efficacious for reducing behaviours that can lead to HIV/STD (e.g.…”

Section: Case Examplementioning

confidence: 99%

“…intervention) in each context. As another example more specific to MH/HIV, Garner and colleagues [15] created two separate clinicaltrials.gov registrations: one for their effectiveness outcomes linked to the psychosocial intervention to address substance use in HIV organizations [28] and one for their implementation outcomes associated with the two implementation strategies they are comparing in their trial [29]. Their clear reporting of implementation outcomes (e.g.…”

Section: Case Examplementioning

confidence: 99%

See 1 more Smart Citation

Navigating grey areas in HIV and mental health implementation science

Harkness,

Giusto,

Hamilton

et al. 2024

J Int AIDS Soc.

View full text Add to dashboard Cite

IntroductionImplementation science (IS) offers methods to systematically achieve the Ending the HIV Epidemic goals in the United States, as well as the global UNAIDS targets. Federal funders such as the National Institutes of Mental Health (NIMH) have invested in implementation research to achieve these goals, including supporting the AIDS Research Centres (ARCs), which focus on high‐impact science in HIV and mental health (MH). To facilitate capacity building for the HIV/MH research workforce in IS, “grey areas,” or areas of IS that are confusing, particularly for new investigators, should be addressed in the context of HIV/MH research.DiscussionA group of IS experts affiliated with NIMH‐funded ARCs convened to identify common and challenging grey areas. The group generated a preliminary list of 19 grey areas in HIV/MH‐related IS. From the list, the authors developed a survey which was distributed to all ARCs to prioritize grey areas to address in this paper. ARC members across the United States (N = 60) identified priority grey areas requiring clarification. This commentary discusses topics with 40% or more endorsement. The top grey areas that ARC members identified were: (1) Differentiating implementation strategies from interventions; (2) Determining when an intervention has sufficient evidence for adaptation; (3) Integrating recipient perspectives into HIV/MH implementation research; (4) Evaluating whether an implementation strategy is evidence‐based; (5) Identifying rigorous approaches for evaluating the impact of implementation strategies in the absence of a control group or randomization; and (6) Addressing innovation in HIV/MH IS grants. The commentary addresses each grey area by drawing from the existing literature (when available), providing expert guidance on addressing each in the context of HIV/MH research, and providing domestic and global HIV and HIV/MH case examples that address these grey areas.ConclusionsHIV/MH IS is key to achieving domestic and international goals for ending HIV transmission and mitigating its impact. Guidance offered in this paper can help to overcome challenges to rigorous and high‐impact HIV/MH implementation research.

show abstract

Section: Case Examplementioning

confidence: 99%

Section: Case Examplementioning

confidence: 99%

Navigating grey areas in HIV and mental health implementation science

Harkness,

Giusto,

Hamilton

et al. 2024

J Int AIDS Soc.

View full text Add to dashboard Cite

show abstract

“…Each participant received a US$25 e-gift card upon completion. The survey assessed background characteristics (e.g., age, biological sex, ethnicity, race, highest level of education), implementation climate using the six-item measure developed and described by Jacobs et al (2014) [42], motivational interviewing knowledge and experience using a twoitem index measure developed for this study and where staff self-rated their current baseline knowledge (0 = no knowledge at all, 1 = knowledgeable to a small extent, 2 = knowledgeable to a moderate extent, 3 = knowledgeable to a great extent) and experience (0 = none, 1 = beginner, 2 = intermediate, 3 = advanced, 4 = expert) using MI, setting-intervention t using the six-item measure developed and described by [43], and organizational readiness for change using the 12-item measure developed and described by Shea et al (2014) [44].…”

Section: Participantsmentioning

confidence: 99%

Testing the incremental effectiveness of pay-for-performance to improve implementation of a motivational interviewing brief intervention for substance use disorders in HIV settings: Results of a parallel cluster-randomized type 3 hybrid trial

Garner,

Tueller,

Bradshaw

et al. 2024

Preprint

View full text Add to dashboard Cite

Background: Substance use disorders (SUDs) have a serious adverse impact on the physical and mental well-being of people with HIV. Previously, using a 39-site dual-randomized type 2 hybrid trial design, findings from the Substance Abuse Treatment to HIV Care Project supported the Implementation and Sustainment Facilitation (ISF) strategy to improve implementation and effectiveness of a motivational interviewing brief intervention (MIBI) for SUD within HIV service settings across the United States (US). Building on this trial, this parallel cluster-randomized type 3 hybrid trial aimed to test the incremental effectiveness of a pay-for-performance (P4P), a form of the “alter incentive/allowance structures” strategy. Methods: Twenty-six HIV service organizations, their staff participants (N=87), and their client participants (N=341) were cluster-randomized to one of two implementation conditions. The control condition included staff-focused training, feedback, and consultation (TFC) and team-focused implementation and sustainment (ISF). The experimental condition included TFC+ISF as well as P4P (TFC+ISF+P4P). P4P used financial incentives to reward MIBI implementation (US$10 per MIBI delivered) and MIBI implementation at or above a pre-defined level of quality (US$10 per demonstration). In addition to these outcomes, past 4-week changes/reductions in client participant’s days of primary substance use and anxiety symptoms were examined. Results: The addition of P4P had a large and significant effect on the number of MIBIs implemented (d=1.30, p<.05) and reduction in anxiety (d=-1.54), but there was no impact on days of substance use. P4P had large effects on MIBI quality (d=1.24) and MIBI implementation effectiveness (d=1.28), but these were not significant (p<.10). Conclusions: P4P is a form of the “alter incentive/allowance structures” strategy. Its function is to reward the implementation of a clinical innovation. Rewarding implementation is consistent with the theory of implementation effectiveness, which suggests implementation climate (i.e., the extent to which implementation is expected, supported, and rewarded) is a key antecedent of implementation effectiveness (i.e., the consistency and quality of implementation). We found that P4P had a significant, positive impact on MIBI implementation in HIV service settings, but client-level outcomes were mixed. Future research should examine the effectiveness of the P4P strategy to improve implementation and sustainment of other evidence-based innovations. Trial registration: ClinicalTrials.gov: NCT04687917. Registered 12/18/2020.

show abstract

“…In response to Curran et al ( 1) "hope to stimulate further thinking and to encourage new design combinations" and the current call for proposed advancements to the effectiveness-implementation HTD, this article also codifies the DIeSEL HTD as a novel HTD with potential to further improve the speed and efficiency of translation, especially during T3 (clinical implementation), but perhaps also as part of T4 (public health) translational research. The DIeSEL HTD was codified for use as part of the NIDA-funded Substance Treatment Strategies for HIV (STS4HIV) Project, which since being funded in 2018 has completed three stakeholder-engaged real-time Delphi (SE-RTD) surveys to empirically identify the substance use disorders with the most negative population-level impact (24), the best fitting evidence-based interventions for integration into HIV service settings (25), and the best fitting strategies for the AIDS Education and Training Centers (AETC) purveyor network to use in helping improve the integration of evidence-based substance use disorder interventions within HIV service settings (26). Organized by aim, below is an overview of the this HTD, which as Figure 1 helps visualize, is essentially a dissemination trial combined with a Type 3 effectiveness-implementation hybrid trial expanded to also combine elements of sustainment research, economic research, and scaling research.…”

Section: The Diesel Hybrid Trial Designmentioning

confidence: 99%

From innovative applications of the effectiveness-implementation hybrid trial design to the dissemination, implementation, effectiveness, sustainment, economics, and level-of-scaling hybrid trial design

Garner

2022

Front.Health Serv.

Self Cite

View full text Add to dashboard Cite

To address the enduring gap between research and practice, there is a need to improve the speed and efficiency of research across the translational research spectrum. In 2012, the effectiveness-implementation hybrid trial design (HTD) was codified as a design with the potential to improve the speed and efficiency of translation, especially as part of T2 (clinical research) translational research. Building on this and other recent efforts to stimulate greater use of this novel HTD, the current article highlights an innovative application of each effectiveness-implementation HTD type. The completed application of the Type 1 effectiveness-implementation HTD tested the effectiveness of a clinical intervention for reducing HIV viral load and retaining people with HIV in care, as well as conducted a longitudinal mixed-methods examination to test for significant changes over time in three key measures of context, and economic evaluation of the clinical intervention. The completed application of the Type 2 effectiveness-implementation HTD used a dual-randomized design to simultaneously test the effectiveness of a clinical intervention for addressing substance use disorder among people with HIV and effectiveness of a blended strategy called the Implementation and Sustainment Facilitation (ISF) Strategy. This Type 2 hybrid trial was also innovative due to its focus on both sustainment and economic outcomes. The innovative Type 3 application (funded in 2008 and completed in 2012) tested the effectiveness and cost-effectiveness of using pay-for-performance to improve both implementation outcomes and client outcomes. This article also codifies a HTD called the Dissemination, Implementation, effectiveness, Sustainment, Economics, and Level-of-scaling (DIeSEL) HTD.

show abstract

The Setting-Intervention Fit of Nine Evidence-Based Interventions for Substance Use Disorders Within HIV Service Organizations Across the United States: Results of a National Stakeholder-Engaged Real-Time Delphi Study

Abstract: Supplemental Digital Content is Available in the Text.

Cited by 4 publications

References 40 publications

Navigating grey areas in HIV and mental health implementation science

Navigating grey areas in HIV and mental health implementation science

Testing the incremental effectiveness of pay-for-performance to improve implementation of a motivational interviewing brief intervention for substance use disorders in HIV settings: Results of a parallel cluster-randomized type 3 hybrid trial

From innovative applications of the effectiveness-implementation hybrid trial design to the dissemination, implementation, effectiveness, sustainment, economics, and level-of-scaling hybrid trial design

Contact Info

Product

Resources

About