The serum protein electrophoretic pattern and acute phase protein concentrations in calves with chronic respiratory diseases

Tóthová, Csilla; Nagy, Oskar; Kováč, G.

doi:10.2478/pjvs-2013-0052

Cited by 7 publications

(7 citation statements)

References 7 publications

(7 reference statements)

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“…22 However, an increase in Hp was also observed to precede abscess formation in goats experimentally infected with Corynebacterium pseudotuberculosis , 21 whereas the SAA level remained unchanged. A significantly higher proportion of cattle with acute inflammation were found to have higher values of SAA and Hp than those with chronic inflammation, 17,20 but in one study 32 both APPs were significantly elevated in calves with chronic respiratory disease. Obviously, a prospective study is warranted to determine changes of APPs in the course of chronic SRLV infection.…”

Section: Discussionmentioning

confidence: 84%

Acute-phase proteins in pregnant goats: a longitudinal study

et al. 2017

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We documented changes in serum amyloid A (SAA) and haptoglobin (Hp) concentration in goats during pregnancy, as measured by competitive ELISAs. Fifteen does (pregnant group) and 20 castrated males (control group) were enrolled in the study. Blood samples were collected on the same day from all 35 goats, 7 times throughout the study period: at mating, then once every month, during the week preceding kidding, and 1 mo after kidding. Baseline SAA and Hp concentrations at mating were identical in the 2 groups. In the pregnant group, SAA concentration rose significantly in the second month and remained elevated until the end of pregnancy, with the peak concentration at kidding. In the control group, SAA concentration remained unchanged compared to the baseline concentration throughout the study. SAA concentration was significantly higher in the pregnant than control group only at the end of the fourth month of pregnancy and at kidding. Hp concentration did not change during pregnancy or between groups. SAA concentration at kidding was affected only by parity of does-it was highest in does in the third and fourth pregnancy and gradually lower in older does.

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Section: Discussionmentioning

confidence: 84%

Acute-phase proteins in pregnant goats: a longitudinal study

et al. 2017

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“…Since many acute phase proteins migrate in the α region, the concentrations of α 1 -and α 2 -globulins may be elevated in acute, as well as chronic inflammatory diseases as a result of the activation of the host inflammatory responses (O'Connell et al 2005). Increased α-globulins (predominantly α 1 -globulins) were found in sheep naturally infected with Babesia ovis, as well as in calves affected by respiratory diseases (Apaydin and Dede 2010;Tothova et al 2013b). The α 2 -globulin fraction typically increases in patients with nephrotic syndrome as a result of the increased synthesis of α 2 -macroglobulin that migrates in this fraction.…”

Section: Globulinsmentioning

confidence: 99%

“…In this study, diseased sheep had significantly lower albumin, and higher α 1 -and γ-globulin concentrations. Recently, Tothova et al (2013b) evaluated the effect of chronic bronchopneumonia on the serum protein pattern in calves. These authors found significantly higher concentrations of α 1 -, β 2 -and γ-globulins in the affected animals compared with healthy ones.…”

Section: The Usefulness Of Serum Protein Electrophoresis In Clinical mentioning

confidence: 99%

Serum proteins and their diagnostic utility in veterinary medicine: a review

Tóthová¹,

Nagy²,

Kováč³

2016

Vet. Med.

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130

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ABSTRACT:The evaluation of serum proteins and their electrophoretic pattern is a well-established laboratory method in the diagnosis of many diseases in humans, which has replaced the biochemical determination of the concentrations of albumin and the ratio of albumin to globulins. The measurement of serum proteins may be an important diagnostic tool for the detection, diagnosis, and monitoring of various diseases and pathological processes. The results of serum protein electrophoresis can be one of the most useful diagnostic aids in a wide spectrum of diseases, including infectious and inflammatory diseases, renal or gastrointestinal disorders, immunodeficiency states, as well as paraproteinaemias caused by lymphoid or plasma cell neoplasia. Although many studies have been carried out to determine the usefulness of the determination of serum proteins and their electrophoretic pattern in various disease conditions and disorders also in animals, serum protein evaluation is still a relatively little-used diagnostic tool in veterinary medicine. In this article, methods of serum protein determination, their diagnostic utility in animal care practice and their different patterns in dysproteinaemias and paraproteinaemias are reviewed.

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“…During the acute phase response, the requirement for amino acids increases for synthesis of acute phase proteins such as haptoglobins which plays important role in alterations in hepatic protein synthesis leading to elevation in globulin levels, thus the production of other proteins such as albumin will be curtailed. The acute phase reaction leads to hyperglobulinemia, hyperproteinemia, hypoalbuminemia and lower albuminglobulin ratio (Tothova et al 2013).…”

Section: Discussionmentioning

confidence: 99%

Prevalence of Respiratory Syncytial Virus Infection in Sheep at Babylon Governorate, Iraq

2022

Int J Vet Sci

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The current study aimed to determine the occurrence of the ovine respiratory syncytial virus (ORSV) infection in sheep employing sandwich enzyme-linked immunosorbent assay (sandwich-ELISA) and look into some disease risk factors. We collected blood samples (n=460) from sheep of various ages and sexes in Babylon Governorate/Iraq. The epidemiological data obtained during the interview with the owners of the animals. The prevalence of ORSV infection at Babylon Governorate was 58.91% based on sandwich-ELISA. The risk factors related to ORSV infection included: sheep with 7months-2years old, imported animals, outdoor feeding, large herd size, in northern parts of the Governorate and winter and spring seasons. There was a significant elevation in RBC, Hb, PCV and a significant reduction in WBC and lymphocytes. There was a significant elevation in AST, CK, LDH, TP, globulin, and total bilirubin. At the same time, there was a significant reduction in albumin, creatinine, and glucose in the infected animals with ORSV. In conclusion, ORSV is prevalent in sheep at Babylon Governorate, with a higher prevalence of the disease in the northern parts of the Governorate. The present report is the first for detecting ORSV antigens in sheep at Babylon Governorate/Iraq.

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The serum protein electrophoretic pattern and acute phase protein concentrations in calves with chronic respiratory diseases

Cited by 7 publications

References 7 publications

Acute-phase proteins in pregnant goats: a longitudinal study

Acute-phase proteins in pregnant goats: a longitudinal study

Serum proteins and their diagnostic utility in veterinary medicine: a review

Prevalence of Respiratory Syncytial Virus Infection in Sheep at Babylon Governorate, Iraq

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