The seroepidemiology of Bordetella pertussis in Israel—Estimate of incidence of infection

Seroprevalence of antibodies against measles, rubella, mumps, varicella-zoster, andB. Pertussisin young adults of Madrid, Spain

“…This increase could be related to differences in the kinetics of PT 36 or to the waning immune response observed 10 to 20 y after natural infection potentially occurring during adolescence, once protection of primary vaccination was lost. 37 The 25 to 29 age group displayed the highest seroprevalence figures. These data coincide with that described in several studies conducted in other countries.…”

“…These data coincide with that described in several studies conducted in other countries. [36][37][38] As value and negative when absorbance values were less than 15% of the cut-off value. Statistical analysis.…”

Pertussis: Microbiology, Disease, Treatment, and Prevention

“…Using the first approach, the annual seroincidence of pertussis among adolescents and adults ranged from one to six percent, and when the second approach was used, the pertussis incidence ranged from one to four percent. Another seroepidemiological study was conducted in a highly vaccinated population (Ͼ93%) in Israel to estimate the magnitude of B. pertussis infections (402). Approximately 2,000 serum samples were analyzed using standardized methods for IgG PT.…”

Prevalence and Molecular Characterization of Pertactin-Deficient Bordetella pertussis in the United States

“…This resurgence has been attributed to many factors, such as improved surveillance capacity, increased awareness among clinicians and the public, more sensitive and specific laboratory diagnostics, and waning protection from the acellular vaccines (3,4). Increased pertussis case counts have been seen in multiple countries with various vaccination programs (5)(6)(7). In the United States, the whole-cell pertussis vaccine was introduced for children in the 1950s and later replaced by an acellular vaccine in the 1990s.…”