The Seizuring Cat

Bailey, Kerry Smith; Dewey, Curtis W.

doi:10.1016/j.jfms.2009.03.006

Cited by 46 publications

(93 citation statements)

References 33 publications

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“…It is reported that all cats with seizures have structural brain disease and as a result of this statement, it was believed for a long time that IE occurs only very rarely in cats . However, a considerable proportion of cats with recurrent seizures show no underlying disease , . In 3 larger retrospective studies, a total of 233 epileptic cats were evaluated and 77 (33%) classified as IE .…”

Section: Etiologic Classification For Catsmentioning

confidence: 99%

“…However, focal epileptic seizures can become generalized so rapidly that their true nature is missed and the seizure might then be classified as primary generalized. The ictus usually lasts for not longer than 3 minutes …”

Section: Diagnostic Evaluation Of a Cat With Suspected Epileptic Seizurementioning

confidence: 99%

“…Historically, focal seizures have been associated with structural brain disease, but there is increasing evidence that focal and generalized seizures occur with nearly equal frequency in IE and SE . In practice, this means that focal seizure does not rule out IE, nor does generalized seizure suggest IE . The situation is actually even less clear, as 40–50% of cats in the IE and SE groups showed both focal and generalized seizures .…”

Section: Diagnostic Evaluation Of a Cat With Suspected Epileptic Seizurementioning

confidence: 99%

See 2 more Smart Citations

Epilepsy in Cats: Theory and Practice

Pákozdy

Halász

Klang

2014

Veterinary Internal Medicne

102

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The veterinary literature on epilepsy in cats is less extensive than that for dogs. The present review summarizes the most important human definitions related to epilepsy and discusses the difficulties in applying them in daily veterinary practice. Epileptic seizures can have a wide range of clinical signs and are not necessarily typical in all cases. Whether a seizure event is epileptic can only be suspected based on clinical, laboratory, and neuroimaging findings as electroencephalography diagnostic techniques have not yet been developed to a sufficiently accurate level in veterinary medicine. In addition, the present review aims to describe other diagnoses and nonepileptic conditions that might be mistaken for epileptic seizures. Seizures associated with hippocampal lesions are described and discussed extensively, as they seem to be a special entity only recognized in the past few years. Furthermore, we focus on clinical work‐up and on treatment that can be recommended based on the literature and summarize the limited data available relating to the outcome. Critical commentary is provided as most studies are based on very weak evidence.

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Section: Etiologic Classification For Catsmentioning

confidence: 99%

Section: Diagnostic Evaluation Of a Cat With Suspected Epileptic Seizurementioning

confidence: 99%

Section: Diagnostic Evaluation Of a Cat With Suspected Epileptic Seizurementioning

confidence: 99%

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Epilepsy in Cats: Theory and Practice

Pákozdy

Halász

Klang

2014

Veterinary Internal Medicne

102

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“…Whereas the etiology and diagnosis of epilepsy show similarities between dogs and cats, treatment with antiepileptic drugs (AEDs) in cats is different than in dogs [3, 4]. …”

Section: Introductionmentioning

confidence: 99%

“…Along with non-fatal adverse events like sedation, polyuria and polydipsia, diazepam has been linked to potentially fatal idiosyncratic hepatotoxicosis, hepatic necrosis and liver failure in cats [10]. Consequently, diazepam is often not considered a viable maintenance oral anticonvulsant option for cats [4, 11]. For the same reason other benzodiazepines like clorazepate are not recommended [12].…”

Section: Introductionmentioning

confidence: 99%

Imepitoin is well tolerated in healthy and epileptic cats

et al. 2017

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Background: Epilepsy in the cat is a serious medical condition. To date there are no licensed treatments for feline epilepsy and no well-controlled clinical studies on the efficacy or safety of antiepileptic drugs in cats. The aim of this study was to collect tolerability data and first exploratory efficacy data of imepitoin in both healthy and epileptic cats. Results: In two tolerability studies, 30 healthy cats received imepition twice daily in doses of 0, 30, 40 or 80 mg/kg bodyweight for 30 days. No serious adverse events were observed in any of the dose groups. In the imepitoin treated groups, emesis was observed in some animals temporarily and intermittently mainly in the second and third weeks of treatment. In a small, single-arm, open label, uncontrolled clinical trial eight cats suffering from idiopathic epilepsy were treated with imepitoin twice daily at doses of 30 mg/kg bodyweight for 30 days. Four of these cats (50%) achieved seizure freedom for at least 8 weeks under treatment. Adverse events, mostly lethargy, decreased appetite and emesis, were often mild and transient. Conclusion: In summary, imepitoin was well tolerated in healthy and epileptic cats and showed in a pilot trial indication for efficacy in treating feline epilepsy.

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Neurologic Emergencies

Herring¹

2014

Handbook of Canine and Feline Emergency Protocols

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The Seizuring Cat

Cited by 46 publications

References 33 publications

Epilepsy in Cats: Theory and Practice

Epilepsy in Cats: Theory and Practice

Imepitoin is well tolerated in healthy and epileptic cats

Neurologic Emergencies

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