The Seasonality of Peripheral Venous Catheter-Related Bloodstream Infections

Abstract

Introduction: Although the seasonality of infectious diseases has been widely reported, the seasonality of peripheral venous catheterrelated bloodstream infection (PV-CRBSI) has not been investigated. This study investigated the seasonality of PV-CRBSI and its relationship with meteorological conditions. Methods: A retrospective cohort study of PV-CRBSI at Tokyo Medical University Hospital (Tokyo, Japan), from 2009 to 2019, provided the data for descriptive and time series analyses used to evaluate the number of PV-CRBSI cases per 1000 admissions that occurred each month for each causative organism. By performing univariate and multivariate analyses, the researchers investigated the seasonality of cases and the relationships between meteorological conditions, other external factors, and PV-CRBSIs. Results: This study included a total of 184 PV-CRBSI cases. The mean numbers of PV-CRBSI cases per 1000 admissions caused by all organisms, Bacillus cereus, Gram-positive cocci, and Gram-negative rods were 0.67, 0.15, 0.37, and 0.16 per month, respectively, during the study period. The time series analysis showed that the incidences of PV-CRBSI cases associated with B. cereus and Gram-negative rods were significantly different in the winter/spring from those in the summer/autumn (P \ 0.05). The incidence of PV-CRBSI cases caused by B. cereus peaked during summer. The incidence of PV-CRBSI cases caused by B. cereus was significantly positively associated with average monthly temperature, whereas the incidence of PV-CRBSIs caused by Gram-negative rods was significantly negatively associated with average daylight hours. Conclusion: The incidence of PV-CRBSIs caused by B. cereus showed seasonality, peaking during the summer, and a significant correlation was found between PV-CRBSIs caused by

Peripheral Parenteral Nutrition Solutions and Bed Bath Towels as Risk Factors for Nosocomial Peripheral Venous Catheter-related Bloodstream Infection by Bacillus cereus

“…The detection rate of B. cereus in blood culture-positive samples is 1.2% according to the information published from the Japan Nosocomial Infections Surveillance (JANIS) in 2020. The rates in A and B Hospitals (736 and 904 beds, respectively) were 1.7 and 22.2%, respectively 28 . It is highly probable that bed bath towels contaminated with B. cereus may have contributed to the high outbreak rates of B. cereus in B Hospitals measured in the blood-culture-positive samples.…”

“…However, an increasing number of studies suggested that B. cereus causes serious septicemia (bacteremia) [6][7][8][9][10][11][12][13][14][15][16][17][18][19][20][21]. In addition, the administration of peripheral parenteral nutrition containing glucose, amino acids, and electrolytes (PPN) [22][23][24][25] and the summer season [26][27][28] have been indicated as risk factors for B. cereus-related septicemia. Of these risk factors, the former was extracted because B. cereus may proliferate in PPN.…”

Prevention of central line‐associated bloodstream infections: ICU nurses' knowledge and barriers

“…2 CLABSI has been a significant challenge in care and has increased health care costs and mortality. [3][4][5] On the other hand, the prevalence of CVC-related infections in the ICU can lead to healthcare-acquired infections (HCAIs). HCAIs are infections that occur within 48 to 72 hours or more after hospitalization.…”

“…Meanwhile, central line‐associated bloodstream infections (CLABSI) are among the most lethal complications associated with CVC use in intensive care units (ICU) 2 . CLABSI has been a significant challenge in care and has increased health care costs and mortality 3–5 . On the other hand, the prevalence of CVC‐related infections in the ICU can lead to healthcare‐acquired infections (HCAIs).…”