The SHH‐GLI1 pathway is required in skin expansion and angiogenesis

Abstract

To investigate the role of GLI1 on skin proliferation and neovascularization during skin expansion in mice. We constructed GLI1-cre/R26-Tdtomato and GLI1-cre/R26mtmg gene-tagged skin expansion mouse models. Using a two-photon in vivo imaging instrument to observe the changes in the number and distribution of GLI1(+) cells dur-How to cite this article: Zhang X, Chen Y, Ding P, et al. The SHH-GLI1 pathway is required in skin expansion and angiogenesis.