The Prl3d1‐Cre mouse line selectively induces the expression of Cre recombinase in parietal trophoblast giant cells
Linqing Pan,
Fuquan Zhu,
Aochen Yu
et al.
Abstract:SummaryThe placenta plays a pivotal role in the maintenance of normal pregnancy, but how it forms, matures, and performs its function remains poorly understood. Here, we describe a novel mouse line (Prl3d1‐iCre) that expresses iCre recombinase under the control of the endogenous prl3d1 promoter. Prl3d1 has been proposed as a marker for distinguishing trophoblast giant cells (TGCs) from other trophoblast cells in the placenta. The in vivo efficiency and specificity of the Cre line were analyzed by interbreeding… Show more
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