2023
DOI: 10.1111/aor.14631
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The NASA artificial heart driver: A pneumatic power source developed for Willem Kolff's artificial heart program

Purab D. Kothari,
Danial Ahmad,
Stephen R. Topaz

Abstract: The sprint to create a viable, implantable heart replacement device started in the 1950s, with current technologies still lacking a permanent solution. Early development of artificial hearts was littered with obstacles related to the power source. A pneumatic driver suggested and developed by NASA aimed to discover a more suitable pressure curve through offering highly manipulable parameters, but also enable automatic regulation of hemodynamics. While improved electric function waveforms were identified, the d… Show more

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“…The artificial heart, as an advanced medical device, is utilized for treating patients with heart failure. It effectively replaces or supports the failing biological heart to restore its function, significantly avoiding issues related to donor shortages and post-transplant immune rejection commonly associated with heart transplantation strategies [1][2][3]. Moreover, a continuous and stable energy supply is one of the critical factors limiting the development of artificial hearts.…”
Section: Introductionmentioning
confidence: 99%
“…The artificial heart, as an advanced medical device, is utilized for treating patients with heart failure. It effectively replaces or supports the failing biological heart to restore its function, significantly avoiding issues related to donor shortages and post-transplant immune rejection commonly associated with heart transplantation strategies [1][2][3]. Moreover, a continuous and stable energy supply is one of the critical factors limiting the development of artificial hearts.…”
Section: Introductionmentioning
confidence: 99%