The <scp>I</scp>rish living kidney donor program – why potential donors do not proceed to live kidney donation?

Connaughton, Dervla M.; Harmon, Grainne; Cooney, Anne; Williams, Yvonne; O’Regan, John; O'Neill, D; Cunningham, Phyllis M.; Counihan, Aileen; O’Kelly, Patrick; McHale, Siobhan; Denton, Mark D.; O’Seaghdha, Conall M.; Magee, Colm; Conlon, Peter J.; Little, Dilly; Keogan, M.; Freitas, D. G. de

doi:10.1111/ctr.12641

Cited by 22 publications

(18 citation statements)

References 17 publications

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“…The majority of the potential donors in our study were young with no significant difference in average age between accepted (29 years) and rejected (31 years) donors, which was similar to the KFSH study where the average age of potential LKDs was 32 years [10]. In contrast, the potential LKDs in our study were younger than LKDs of other studies from western countries where the average age was between 45 to 53 years [12,13]. Also, our study showed that both groups were predominantly males (79.6% vs. 86.3%).…”

Section: Discussionsupporting

confidence: 80%

Why Living Kidney Donor Candidates Are Turned Down? A Single-Center Cohort Study

Altheaby

Almukhlifi

Aldoukhi

et al. 2020

Cureus

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Section: Discussionsupporting

confidence: 80%

Why Living Kidney Donor Candidates Are Turned Down? A Single-Center Cohort Study

Altheaby

Almukhlifi

Aldoukhi

et al. 2020

Cureus

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“…Two UK single-centre cohort studies have reported the proportion of potential donors that actually go on to donate as 13% 3 and 18%. 4 Studies from the Republic of Ireland, 5 the Netherlands, 6 Poland, 7 South Africa, 8 and the USA, [9][10][11] have reported varied estimates of between 8-49% of potential donors becoming actual donors. Almost all of these studies were single-centre and the predictors of donation and of non-donation have not been well described.…”

Section: Introductionmentioning

confidence: 99%

A multicenter cohort study of potential living kidney donors provides predictors of living kidney donation and non-donation

Bailey

Tomson

MacNeill

et al. 2017

Kidney International

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This multicenter prospective potential living kidney donor cohort study investigated which sociodemographic and other factors predict progression to living kidney donation or donor withdrawal as little is known on this topic. Therefore, we examined data on individuals undergoing living donor assessment at seven hospitals in the United Kingdom. Multivariable logistic regression was used to explore the relationships between donor and recipient characteristics and likelihood of kidney donation. A total of 805 individuals presented for directed donation to 498 intended recipients, of which 112 received a transplant from a living donor. Potential donors were less likely to donate if their intended recipient was female rather than male with an odds ratio of 0.60, a friend rather than relative 0.18, or had renal failure due to a systemic disease rather than another cause 0.41. The most socioeconomically deprived quintile was less likely to donate than the least 0.49, but the trend with deprivation was consistent with chance. Higher body mass index was associated with a lower likelihood of donation (odds ratio per each kg/m increase, 0.92). Younger potential donors (odds ratio per each year increase 0.97), those of nonwhite ethnicity 2.98, and friend donors 2.43 were more likely to withdraw from work-up. This is the first study in the United Kingdom of potential living kidney donors to describe predictors of non-donation. Qualitative work with individuals who withdraw might identify possible ways of supporting those who wish to donate but experience difficulties doing so.

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“…These factors acted as actual controls and impacted the donation behavior. A considerable number of living donor drop-out, observed at the initial stages, could be related in part related to medical contraindications [21,22].…”

Section: Discussionmentioning

confidence: 99%

Perception of Healthcare Workers about Barriers Impacting Organ Donation in Qatar: A Focus Group Study

Agarwal

Singh

Thani

et al. 2018

OSJ

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Objectives: To understand perception of healthcare workers about factors acting as barriers to organ donation and transplantation process in Qatar. Subjects and Methods: A phenomenological approach with the help of focus group discussions was used to fulfill the objectives of the research. Participants were healthcare workers working as volunteers in organ donation campaigns or playing a crucial role in the process of organ donation or transplantation in Qatar. They were selected purposively to participate in the discussions. Openended questions were asked during the audio-recorded discussions. Transcripts were coded and assessed using NVivo software. Results were analyzed based on the Theory of Planned Behavior to explore intentions shaping an individual's donation decision. Results: Lack of awareness and information about the process of organ donation were found to be the root cause barriers for both deceased and living organ donation in Qatar whereas; family, religious and community influences, and an incongruous attitude towards organ donation are the main factors influencing organ donation registration and family consent for deceased donation. Conclusion: Improving awareness and accurate information about organ donation could play significant in increasing deceased and living organ donation in Qatar. However, factors impacting family consent, which was found to be the most prominent reason for gap between availability and utilization of organs, need to be further researched.

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The Irish living kidney donor program – why potential donors do not proceed to live kidney donation?

Abstract: Further evaluation of the declined donor group is warranted to allow for expansion of the LD program.

Cited by 22 publications

References 17 publications

Why Living Kidney Donor Candidates Are Turned Down? A Single-Center Cohort Study

Why Living Kidney Donor Candidates Are Turned Down? A Single-Center Cohort Study

A multicenter cohort study of potential living kidney donors provides predictors of living kidney donation and non-donation

Perception of Healthcare Workers about Barriers Impacting Organ Donation in Qatar: A Focus Group Study

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