The <scp>Generalized Anxiety Disorder Screener (GAD‐7</scp>) and the anxiety module of the <scp>Hospital and Depression Scale (HADS‐A</scp>) as screening tools for generalized anxiety disorder among cancer patients

Esser, Peter; Hartung, Tim; Friedrich, Michael; Johansen, Christoffer; Wittchen, Hans‐Ulrich; Faller, Hermann; Koch, Uwe; Härter, Martin; Keller, Monika; Schulz, Holger; Wegscheider, Karl; Weis, Joachim; Mehnert, Anja

doi:10.1002/pon.4681

Cited by 118 publications

(94 citation statements)

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“…Based on a subsample of this cancer patients' sample, the HADS anxiety and depression scores have already been analysed concerning the prediction of generalised anxiety disorders (Esser et al, 2018) and major depression (Hartung et al, 2017). The study was conducted in accordance with the Declaration of Helsinki and was approved by the ethics committees of all participating centres.…”

Section: Cancer Patientsmentioning

confidence: 99%

“…Depressed patients have a higher mortality rate than non-depressed patients (Mols, Husson, Roukema, & Poll-Franse, 2013;Pinquart & Duberstein, 2010). Multiple studies have been performed to test the reliability and validity of the HADS (Bjelland, Dahl, Haug, & Neckelmann, 2002;Herrmann, 1997), especially in cancer populations (Esser et al, 2018;Hartung et al, 2017;Mitchell, Meader, & Symonds, 2010;Vodermaier & Millman, 2011). One frequently used questionnaire is the Hospital Anxiety and Depression Scale (HADS) (Zigmond & Snaith, 1983).…”

Section: Introductionmentioning

confidence: 99%

“…One frequently used questionnaire is the Hospital Anxiety and Depression Scale (HADS) (Zigmond & Snaith, 1983). Multiple studies have been performed to test the reliability and validity of the HADS (Bjelland, Dahl, Haug, & Neckelmann, 2002;Herrmann, 1997), especially in cancer populations (Esser et al, 2018;Hartung et al, 2017;Mitchell, Meader, & Symonds, 2010;Vodermaier & Millman, 2011). A review article comparing various patient-reported outcome measures of anxiety and depression used in RCTs with cancer patients found that the HADS scored best overall (Luckett et al, 2010).…”

Section: Introductionmentioning

confidence: 99%

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Age and gender differences in anxiety and depression in cancer patients compared with the general population

Hinz

Herzberg

Lordick³

et al. 2019

Eur J Cancer Care

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Objective:The aim of this study was to compare the levels of anxiety and depression in cancer patients with those of the general population, to examine age and gender differences in anxiety and depression, to analyse the impact of several sociodemographic and clinical parameters on anxiety and depression, and to test the age and gender measurement invariance of the Hospital Anxiety and Depression Scale (HADS).Methods: A sample of 3,785 German patients with cancer and a sample of 2,747 people of the German general population were examined using the HADS. Results:Patients with cancer were more anxious but slightly less depressed than age-and gender-matched individuals of the general population. Young patients with cancer were particularly affected by anxiety. Measurement invariance across gender and age could be established. For all analysed clinical variables, including tumour site, tumour stage, metastases, setting and Eastern Cooperative Oncology Group (ECOG) performance status we found no significant interaction effects with gender that exceeded the 5% significance criterion. Conclusion:The HADS provides fair comparisons between age and gender groups.Gender differences in anxiety and depression can be generalised across the cancer sites and clinical subgroups. Young patients with cancer deserve special attention by the healthcare system.

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Section: Cancer Patientsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Age and gender differences in anxiety and depression in cancer patients compared with the general population

Hinz

Herzberg

Lordick³

et al. 2019

Eur J Cancer Care

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“…Screening tools used previously have included a Distress Thermometer or Cancer Worry Scale, but as we could not predict whether depression or anxiety would predominate in our study patients, we chose to screen using both the Patient Health Questionnaire‐9 (PHQ‐9) depression and Generalized Anxiety Disorder (GAD‐7) questionnaires. These questionnaires have been demonstrated to be sensitive and reliable tools for cancer survivorship . Patients also completed EORTC QLQ‐C30 and OV28 questionnaires so that any depression/anxiety scores could be correlated with general Quality of Life (QOL) measures.…”

Section: Introductionmentioning

confidence: 99%

“…These questionnaires have been demonstrated to be sensitive and reliable tools for cancer survivorship. 14,15 Patients also completed EORTC QLQ-C30 and OV28 questionnaires so that any depression/anxiety scores could be correlated with general Quality of Life (QOL) measures.…”

mentioning

confidence: 99%

New challenges in psycho‐oncology: Using drug development methodology to improve survivorship and supportive care intervention trials

Howells¹,

Hulbert‐Williams

Blagden

2019

Psycho-Oncology

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Mental health status of the general population, healthcare professionals, and university students during 2019 coronavirus disease outbreak in Jordan: A cross‐sectional study

et al. 2020

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Background The emergence of COVID‐19 global pandemic coupled with high transmission rate and mortality has created an unprecedented state of emergency worldwide. This global situation may have a negative impact on the psychological well‐being of individuals which in turn impacts individuals' performance. This study aims to explore the prevalence of depression and anxiety among the GP, HCPs, and USs during COVID‐19 outbreak, and to identify key population(s) who might need psychological intervention. Methods A cross‐sectional study using an online survey was conducted in Jordan between 22 and 28 March 2020 to explore the mental health status (depression and anxiety) of the general population, healthcare professionals, and university students during the COVID‐19 outbreak. The Patient Health Questionnaire (PHQ‐9) and Generalized Anxiety Disorder‐7 (GAD‐7) were used to assess depression and anxiety among the study participants. Logistic regression analysis was used to identify predictors of depression and anxiety. Results The prevalence of depression and anxiety among the entire study participants was 23.8% and 13.1%, respectively. Anxiety was most prevalent across university students 21.5%, followed by healthcare professionals 11.3%, and general population 8.8%. Females among healthcare professionals and university students, divorced healthcare professionals, pulmonologists, and university students with history of chronic disease were at higher risk of developing depression. Females, divorced participants among the general population, and university students with history of chronic disease and those with high income (≥1,500 JD) were at higher risk of developing anxiety. Conclusions During outbreaks, individuals are put under extreme stressful condition resulting in higher risk of developing anxiety and depression particularly for students and healthcare professionals. Policymakers and mental healthcare providers are advised to provide further mental support to these vulnerable groups during this pandemic.

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The Generalized Anxiety Disorder Screener (GAD‐7) and the anxiety module of the Hospital and Depression Scale (HADS‐A) as screening tools for generalized anxiety disorder among cancer patients

Abstract: The GAD-7 and HADS-A showed AUC of adequate diagnostic accuracy and hence are applicable for GAD screening in cancer patients. Nevertheless, the choice of optimal cut-offs should be carefully evaluated.

Cited by 118 publications

References 36 publications

Age and gender differences in anxiety and depression in cancer patients compared with the general population

Age and gender differences in anxiety and depression in cancer patients compared with the general population

New challenges in psycho‐oncology: Using drug development methodology to improve survivorship and supportive care intervention trials

Mental health status of the general population, healthcare professionals, and university students during 2019 coronavirus disease outbreak in Jordan: A cross‐sectional study

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