The Scandinavian baltic pancreatic club (SBPC) database: design, rationale and characterisation of the study cohort

Olesen, Søren Maagaard; Poulsen, Jakob Lykke; Drewes, Asbjørn Mohr; Frøkjær, Jens Brøndum; Laukkarinen, Johanna; Parhiala, Mikael; Rix, Iben; Novovic, Srdan; Lindkvist, Björn; Bexander, Louise; Engjom, Trond; Erchinger, Friedemann; Haldorsen, Ingfrid S.; Puķītis, Aldis; Ozola-Zālīte, Imanta; Haas, Stephan; Vujasinović, Miroslav; Löhr, Matthias; Gulbinas, Antanas; Jensen, Nanna M.; Jørgensen, Maiken Thyregod; Nøjgaard, Camilla; Club, Scandinavian Baltic Pancreatic

doi:10.1080/00365521.2017.1322138

Cited by 41 publications

(31 citation statements)

References 30 publications

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“…17 Data for the present study were derived from the database as of January 1, 2019, and included data from 11 centers in seven countries in the Scandinavian-Baltic region and Russia (Moscow). The SBPC database is an open multicenter prospective registration of patients with CP with continuously recruitment.…”

Section: Methodsmentioning

confidence: 99%

“…The SBPC database is an open multicenter prospective registration of patients with CP with continuously recruitment. 17 Data for the present study were derived from the database as of January 1, 2019, and included data from 11 centers in seven countries in the Scandinavian-Baltic region and Russia (Moscow). The detailed study protocol and methodology of the SBPC database has previously been published.…”

Section: Methodsmentioning

confidence: 99%

“…The detailed study protocol and methodology of the SBPC database has previously been published. 17 CP was defined according to the M-ANNHEIM classification system, and both patients with definitive and probable CP were included. 18 Patients with a history of pancreatic cancer were excluded.…”

Section: Methodsmentioning

confidence: 99%

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Association of multiple patient and disease characteristics with the presence and type of pain in chronic pancreatitis

Olesen¹,

Kuhlmann

Novovic

et al. 2019

J of Gastro and Hepatol

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Background and Aim Pain is the primary symptom of chronic pancreatitis (CP) and associates with a number of patient and disease characteristics. However, the complex interrelations of these parameters are incompletely understood, and pain treatment remains unsatisfactory in a large proportion of patients. The aim of this study is to investigate multiple pain risk factors in a large population of CP patients, with a special emphasis on patients' patterns of smoking and alcohol use. Methods This was a multicenter, cross‐sectional study including 1384 patients with CP. Patient demographics and disease characteristics, as well as current patterns of smoking and alcohol use, were compared for patients with pain (n = 801) versus without pain (n = 583). Multivariate logistic regression models were performed to assess the variables associated with the presence and type of pain (constant vs intermittent pain). Results The mean age of participants was 52.1 ± 14.6 years, and 914 (66%) were men. Active smoking (odds ratio 1.6 [95% confidence interval 1.1–2.2], P = 0.005) and alcohol consumption (odds ratio 1.8 [95% confidence interval 1.1–3.0], P = 0.03) were independently associated with the presence of pain. In addition, patients' age at diagnosis, pancreatic duct pathology, and the presence of pseudocysts, duodenal stenosis, and exocrine pancreatic insufficiency were confirmed as pain risk factors (all P ≤ 0.01). Constant pain, as opposed to intermittent pain, was more frequently reported by smokers (P = 0.03), while alcohol consumption was associated with intermittent pain (P = 0.006). Conclusion Multiple patient and disease characteristics, including patterns of smoking and alcohol consumption, associate with the presence and type of pain in patients with CP.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

See 1 more Smart Citation

Association of multiple patient and disease characteristics with the presence and type of pain in chronic pancreatitis

Olesen¹,

Kuhlmann

Novovic

et al. 2019

J of Gastro and Hepatol

Self Cite

View full text Add to dashboard Cite

show abstract

“…In recent cross-sectional studies, the proportion of patients who reported having pain ranges from 63 to 86%, suggesting that a subset of patients were pain free at the time of assessment 2, 4, 6, 7, 50 . Variability of pain experience was captured in a large multicenter US study of >500 patients – in the year preceding enrollment, 16% patients reported no pain, 53% reported constant and 32% intermittent pain; pain was mild-moderate in 18% and severe 67% patients.…”

Section: Introductionmentioning

confidence: 99%

“…Narcotics was used intermittently by 23% and constantly by 36%. Interestingly, the proportion of patients treated with narcotics is much lower in Europe (stronger opioids used in 31%) 6 .…”

Section: Introductionmentioning

confidence: 99%