The "Sapho" Syndrome: A Case Report of a Patient With an Accidental Finding of Hyperostosis in Plain X-Rays of Thorax

Abstract

The authors describe the clinical, bone scintigraphy, and histopathologic findings of chronic recurrent multifocal osteomyelitis (CRMO), which is considered to be part of the SAPHO (synovitis, acne, pustulosis, hyperostosis, and osteitis) syndrome. Knowledge of this disorder may help in the differential diagnosis of arthritis, and it will help avoid repeated biopsies. We report the case of a 52-year-old man who was admitted to hospital due to an accidental finding in plain X-rays during his first check-up of his health status. He underwent laboratory tests, imaging examinations, and biopsy and histopathologic examinations of bone tissue; and was diagnosed with the SAPHO syndrome (CRMO).