The safety and efficacy of autologous fat grafting during second stage breast reconstruction

Patel, Ashraf A.; Martin, Shanique; Lee, Gordon K.; Nazerali, Rahim

doi:10.1016/j.bjps.2020.10.008

Cited by 5 publications

(2 citation statements)

References 21 publications

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“…Initially, 292 articles were screened by title and abstract. However, only 48 articles were assessed for full-text eligibility, and among those, 12 studies were eventually included [14][15][16][17][18][19][20][21][22][23][24]. Of the 36 articles excluded after full-text reading, the majority were rejected due to a lack of clear extractable data on hybrid breast reconstruction and mentioned complications.…”

Section: Resultsmentioning

confidence: 99%

Outcomes in Hybrid Breast Reconstruction: A Systematic Review

et al. 2022

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Background and Objectives: Lipofilling is a commonly performed procedure worldwide for breast augmentation and correction of breast contour deformities. In breast reconstruction, fat grafting has been used as a single reconstructive technique, as well as in combination with other procedures. The aim of the present study is to systematically review available studies in the literature describing the combination of implant-based breast reconstruction and fat grafting, focusing on safety, complications rate, surgical sessions needed to reach a satisfying reconstruction, and patient-reported outcomes. Materials and Methods: We adhered to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) throughout the whole review protocol. A systematic review of the literature up to April 2022 was performed using Medline, Embase, and Cochrane Library databases. Only studies dealing with implant-based breast reconstruction combined with fat grafting were included. Results: We screened 292 articles by title and abstract. Only 48 articles were assessed for full-text eligibility, and among those, 12 studies were eventually selected. We included a total of 753 breast reconstructions in 585 patients undergoing mastectomy or demolitive breast surgeries other than mastectomy (quadrantectomy, segmentectomy, or lumpectomy) due to breast cancer or genetic predisposition to breast cancer. Overall, the number of complications was 60 (7.9%). The mean volume of fat grafting per breast per session ranged from 59 to 313 mL. The mean number of lipofilling sessions per breast ranged from 1.3 to 3.2. Conclusions: Hybrid breast reconstruction shows similar short-term complications to standard implant-based reconstruction but with the potential to significantly decrease the risk of long-term complications. Moreover, patient satisfaction was achieved with a reasonably low number of lipofilling sessions (1.7 on average).

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Section: Resultsmentioning

confidence: 99%

Outcomes in Hybrid Breast Reconstruction: A Systematic Review

et al. 2022

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“… 9 , 10 In addition, AFG can also alleviate patients’ depression and anxiety about appearance, thereby regulating mental health and improving quality of life. 11 Although many recent literatures have demonstrated the oncologic safety of AFG following BCS, 12–14 there are still controversial reports on the risk of cancer recurrence with AFG. Particularly, few studies have been focused on the immediate AFG combined with BCS in breast cancer patients.…”

Section: Introductionmentioning

confidence: 99%

Effects of Breast-Conserving Surgery Combined with Immediate Autologous Fat Grafting on Oncologic Safety, Satisfaction and Psychology in Patients with Breast Cancer: A Retrospective Cohort Study

Gong

Zhou

Niu

et al. 2022

CMAR

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Purpose Autologous fat grafting (AFG) is a technique that can improve the appearance of breasts in surgical patients. There are currently few studies on breast-conserving surgery (BCS) combined with immediate AFG, although we believe that it could achieve satisfactory effects. Therefore, the purpose of this study is to observe the effects of BCS combined with immediate AFG on oncologic safety, satisfaction and psychology of breast cancer patients. Patients and Methods We retrospectively collected the data of 85 breast cancer patients from February 2018 to October 2018. After screening, 40 patients in AFG group (AG, BCS combined with immediate AFG) and 40 patients in control group (CG, BCS alone) were finally included in the study. The primary outcomes were the survival, tumor recurrence and metastasis, and BREAST-Q score of patients. The secondary outcomes were short and long-term complications, degree of depression and anxiety of patients. Results A total of 80 patients were included in the analysis. There was no significant difference in the clinicopathological data between the two groups ( P >0.05). The average follow-up time of the two groups was 40.58±2.630 and 40.28±2.679 months. In the analysis of oncologic safety, no patients died in AG and 1 patient died in CG. In addition, there was no significant difference between the two groups in terms of the overall recurrence rate and the distribution of recurrence types ( P >0.05). As for satisfaction, the BREAST-Q score of AG was significantly higher than that of CG (57.85±4.833 vs 51.93±5.045, P <0.001). In the secondary outcomes, there was no short-term complication specified in the study; in the long-term complications, the incidence of calcification in AG was not significantly higher than that in CG ( P =0.065). In the analysis of depression and anxiety, there was no significant difference between the two groups ( P >0.05). Conclusion BCS combined with immediate AFG can significantly improve patients’ satisfaction without increasing the risk of death and tumor recurrence. However, it does not seem to play a role in improving the conditions of depression and anxiety.

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Correction of breast asymmetry by autologous fat grafting with the aid of 3D laser-scanning technology

Wei

Zhang

et al. 2023

Asian Journal of Surgery

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The safety and efficacy of autologous fat grafting during second stage breast reconstruction

Cited by 5 publications

References 21 publications

Outcomes in Hybrid Breast Reconstruction: A Systematic Review

Outcomes in Hybrid Breast Reconstruction: A Systematic Review

Effects of Breast-Conserving Surgery Combined with Immediate Autologous Fat Grafting on Oncologic Safety, Satisfaction and Psychology in Patients with Breast Cancer: A Retrospective Cohort Study

Correction of breast asymmetry by autologous fat grafting with the aid of 3D laser-scanning technology

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