The root cause analysis on failed patient‐specific measurements of pencil beam scanning protons using a 2D detection array with finite size ionization chambers

Ricci, Jacob; Hsi, W. C.; Su, Zhong; Mund, Karl; Dawson, R.; Indelicato, Daniel J.

doi:10.1002/acm2.13343

Cited by 1 publication

(1 citation statement)

References 24 publications

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“…Because of this, a distance to agreement (DTA) in the depth direction was considered to account for any uncertainties associated with depth positioning. Planar 2D gamma analyses were carried out using criteria of 3%/3 mm, 3%/2 mm, and 2%/2 mm to evaluate the expected agreement range, however, the 3%/ 3 mm criterion is widely adopted clinically for PBS proton therapy [35,[39][40][41]. A dose threshold of 10% was used in all gamma analyses to compute the pass rate, following the recommendations of AAPM Task Group 218 for photon-based intensity modulated radiation therapy quality assurance (QA) [42].…”

Section: Experimental Dosimetrymentioning

confidence: 99%

Integration and dosimetric validation of a dynamic collimation system for pencil beam scanning proton therapy

Nelson,

Culberson,

Hyer

et al. 2023

Biomed. Phys. Eng. Express

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Objective. To integrate a Dynamic Collimation System (DCS) into a pencil beam scanning (PBS) proton therapy system and validate its dosimetric impact. Approach. Uncollimated and collimated treatment fields were developed for clinically relevant targets using an in-house treatment plan optimizer and an experimentally validated Monte Carlo model of the DCS and IBA dedicated nozzle (DN) system. The dose reduction induced by the DCS was quantified by calculating the mean dose in 10- and 30-mm two-dimensional rinds surrounding the target. A select number of plans were then used to experimentally validate the mechanical integration of the DCS and beam scanning controller system through measurements with the MatriXX-PT ionization chamber array and EBT3 film. Absolute doses were verified at the central axis at various depths using the IBA MatriXX-PT and PPC05 ionization chamber. Main results. Simulations demonstrated a maximum mean dose reduction of 12% for the 10 mm rind region and 45% for the 30 mm rind region when utilizing the DCS. Excellent agreement was observed between Monte Carlo simulations, EBT3 film, and MatriXX-PT measurements, with gamma pass rates exceeding 94.9% for all tested plans at the 3%/2 mm criterion. Absolute central axis doses showed an average verification difference of 1.4% between Monte Carlo and MatriXX-PT/PPC05 measurements. Significance. We have successfully dosimetrically validated the delivery of dynamically collimated proton therapy for clinically relevant delivery patterns and dose distributions with the DCS. Monte Carlo simulations were employed to assess dose reductions and treatment planning considerations associated with the DCS.

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Section: Experimental Dosimetrymentioning

confidence: 99%

Integration and dosimetric validation of a dynamic collimation system for pencil beam scanning proton therapy

Nelson,

Culberson,

Hyer

et al. 2023

Biomed. Phys. Eng. Express

View full text Add to dashboard Cite

show abstract

The root cause analysis on failed patient‐specific measurements of pencil beam scanning protons using a 2D detection array with finite size ionization chambers

Abstract: This is an open access article under the terms of the Creat ive Commo ns Attri bution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

Cited by 1 publication

References 24 publications

Integration and dosimetric validation of a dynamic collimation system for pencil beam scanning proton therapy

Integration and dosimetric validation of a dynamic collimation system for pencil beam scanning proton therapy

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