The Romanian Marine Ecosystem - an Important Source for the Pharmaceutical Industry

Marine Algae from Black Sea - Important Resources in the Pharmaceutical and Medical Research

“…Out of the vegetal sample sprinkled with a non-polar solvent (ethylic ether, petroleum ether, benzene, hexane, clorophorm etc), then with a medium polarity solvent (ethanol, methanol) and only in the ned with water, the following fractions were obtained, [6,7,8]: As a follow up of the identification reactions previously discussed, the following results were obtained, summarized in Table 1, 2, 3, 4.  a fraction of the etheric extract was evaporated up to dryness; the residuum obtained was dissolved in alcohol -the resulting solution does not have the specific smell of volatile oils for any of the algae species;  the residuum obtained from the evaporation of the etheric extract was processed with HCl 2%; the solution undertook the Mayer and Bertrand reactions; the reactions were negative; the analyzed algae do not contain basic alcaloids;  the residuum obtained from the evaporation of the etheric extract was processed with methilic alcohol; the alcoholic solution undertook the Shibata reactions; the reaction was negative for all algae species, which do not contain flavonoic aglicones  the residuum obtained from the evaporation of the etheric extract was processed with amonium hydroxyde; the Borntrager reactive did not colout the solution orange; the analyzed algae do not contain endemoles;  the Lieberman -Burchard reaction on the etheric extract was positive, indicating the presence of steroles and triterpenes in all analyzed algae;  the Carr -Price reaction was positive, thus they contain carotenoids, for the species Cladophora vagabunda, Ulva rigida, and negative for the other species;  the residuum obtained from the evaporation of the etheric extract was processed with amonium hydroxyde; the solution did not present an intense fluorescence on UV radiation, thus no species contains cumarines.…”

Marine Algae from Black Sea - Important Resources in the Pharmaceutical and Medical Research

“…The microscopic exam of the collected algae was realized through the use of specific for the pharmacobotanical researches, [5,6]. For the global chemical analysis, the extraction of the active principles is very important [6,7,8]. The qualitative chemical analysis involves the successive and selective analysis of the vegetal products, using solvents with opposing polarities, and the separation by the means of chemical methods, followed by specific reactions which help to identify different groups of active principles or certain chemical constituents [7].…”

“…Out of the vegetal sample sprinkled with a non-polar solvent (ethylic ether, petroleum ether, benzene, hexane, clorophorm etc), then with a medium polarity solvent (ethanol, methanol) and only in the ned with water, the following fractions were obtained, [6,7,8]:…”

“…From the read and brwoun algae we have Ceramium rubrum and Cystoseira barbata. From the green algae of the Black Sea, the systemic clasification of the Class Chlorophyceae was presented [5,6,7]. The methods are from botanical phytochemical and physico-chemical area.…”

Heavy Metals Existing in the Seaweed from the Romanian Coast of the Black Sea

“…Marine algae have been intensely studied [1] In the context of restructured economic activities and of increased exigencies with respect to the implementation of environment politics, a slight but continuous recovery process of the marine ecosystem has been taking place during last years. The superior exploitation of the marine biomass represents a highly important resource for the pharmaceutical industry, supplying raw material for the extraction of bioactive substances (vitamins, sterols, and aminoacids) and various other substances, the purity of which is strongly connected to the state of the marine ecosystem [2,3]. Several studies regarding marine habitats where large amounts of seaweed can be found have been conducted [4,5,6].…”