The roles of long noncoding RNAs in atrial fibrillation

MiRNAs as new potential biomarkers and therapeutic targets in brain metastasis

“…Their function involves binding to complementary sites on the 3′ untranslated region (UTR) of genes, leading to the recruitment of protein complexes that hinder translation and/or decrease mRNA stability. MicroRNAs are vital for protein expression and are closely linked to both normal and abnormal biological processes [ [7] , [8] , [9] , [10] , [11] ]. The altered expression of microRNAs in cancer cells compared to normal cells has sparked interest in using microRNA profiling to identify cancer cell origin and assess therapy response.…”

The role of lncRNA-mediated ceRNA regulatory networks in liver fibrosis

“…Similarly, microRNAs (miRNAs) are recognized for their ability to either promote or alleviate liver fibrosis by affecting these pathways [ [12] , [13] , [14] , [15] , [16] , [17] , [18] ]. Long non-coding RNAs (lncRNAs) are RNA molecules arbitrarily defined as those longer than 200 nucleotides, primarily for practical reasons related to RNA purification protocols that typically exclude smaller RNAs [ 19 ]. These lncRNAs serve as critical intermediaries in transmitting information from higher-order chromosomal interactions to modifications in chromatin structure.…”