The Roles of Auxin Biosynthesis YUCCA Gene Family in Plants

Cao, Xu; Yang, Honglei; Shang, Chunqiong; Ma, Sang; Liu, Li; Cheng, Jialing

doi:10.3390/ijms20246343

Cited by 125 publications

(77 citation statements)

References 164 publications

(293 reference statements)

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“…Specifically, all 10 remaining YUCCAs (YUC 2-11) from Arabidopsis have been characterized [52,55,[59][60][61][62][63], as well as other plant species, including the orthologue FLOOZY from petunia (Petunia X hybrida) [64] and fourteen orthologues from rice (OsYUCCA 1-14; Oryza sativa) [65,66]. YUCCA genes have also been characterized from tomato (Solanum lycopersicum) [67], maize (Zea mays) [68], potato (Solanum tuberosum) [69], strawberry (Fragaria vesca) [70] and cucumber (Cucumis sativus L.) [71] (see [72] for full list). To date, all characterized YUCCAs have been shown to be involved in auxin biosynthesis, catalyzing the oxidative decarboxylation reaction of IPA to form IAA.…”

Section: Yuccasmentioning

confidence: 99%

The “Green” FMOs: Diversity, Functionality and Application of Plant Flavoproteins

Thodberg

Neilson

2020

Catalysts

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Flavin-dependent monooxygenases (FMOs) are ancient enzymes present in all kingdoms of life. FMOs typically catalyze the incorporation of an oxygen atom from molecular oxygen into small molecules. To date, the majority of functional characterization studies have been performed on mammalian, fungal and bacterial FMOs, showing that they play fundamental roles in drug and xenobiotic metabolism. By contrast, our understanding of FMOs across the plant kingdom is very limited, despite plants possessing far greater FMO diversity compared to both bacteria and other multicellular organisms. Here, we review the progress of plant FMO research, with a focus on FMO diversity and functionality. Significantly, of the FMOs characterized to date, they all perform oxygenation reactions that are crucial steps within hormone metabolism, pathogen resistance, signaling and chemical defense. This demonstrates the fundamental role FMOs have within plant metabolism, and presents significant opportunities for future research pursuits and downstream applications.

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Section: Yuccasmentioning

confidence: 99%

The “Green” FMOs: Diversity, Functionality and Application of Plant Flavoproteins

Thodberg

Neilson

2020

Catalysts

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“…Plant hormone auxin is known to regulate various developmental and physiological processes (Cao et al, 2019). Among the genes whose expression is regulated by OsBBM1, we find members of the YUCCA family of auxin biosynthesis genes and some auxin response factors (Supplemental Data Set S1).…”

Section: Osbbm1 Upregulates Expression Of Auxin Biosynthesis Genesmentioning

confidence: 99%

“…YUCCA (YUC) genes encode flavin-containing monooxygenase enzymes that catalyze the rate-limiting step of oxidative decarboxylation of indole-3-pyruvate acid during auxin biosynthesis to form indole-3-acetic acid (IAA), the predominant auxin found in plants (Cao et al, 2019). The Arabidopsis genome encodes 11 YUCCA genes, whereas 14 members of this family have been identified in rice (Gallavotti et al, 2008).…”

Section: Introductionmentioning

confidence: 99%

“…The Arabidopsis genome encodes 11 YUCCA genes, whereas 14 members of this family have been identified in rice (Gallavotti et al, 2008). YUC gene mediated auxin biosynthesis has been shown to play diverse roles during various phases of plant development and response to environmental changes (Cao et al, 2019). YUC genes have been shown to regulate root and shoot development (Chen et al, 2014;Zhang et al, 2018), leaf morphogenesis (Cheng et al, 2006(Cheng et al, , 2007, inflorescence development (Woodward et al, 2005;Gallavotti et al, 2008), floral organ development (Cheng et al, 2006), establishment of the embryonic axis (Robert et al, 2013) and embryo organ initiation (Cheng et al, 2007).…”

Section: Introductionmentioning

confidence: 99%

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Rice embryogenic trigger BABY BOOM1 promotes somatic embryogenesis by upregulation of auxin biosynthesis genes

Khanday

Santos‐Medellín

Sundaresan

2020

Preprint

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Somatic embryogenesis, a powerful tool for clonal propagation and for plant transformation, involves cellular reprogramming of differentiated somatic cells to acquire pluripotency. Somatic embryogenesis can be induced by treating explants with plant growth regulators. However, several plant species including agronomically important cereal crops remain recalcitrant to dedifferentiation and transformation except from embryonic tissues. Somatic embryogenesis can also be induced by ectopic expression of select embryonic factors, including in cereals by BABY BOOM (BBM) transcription factors. How BBM genes bypass the need for exogenous hormones is not well understood. Here, we investigated downstream targets during induction of somatic embryogenesis in rice by OsBBM1 ((Oryza sativa BABY BOOM1). Transient induction of OsBBM1 led to the upregulation of auxin biosynthesis OsYUCCA genes. Continued induction of OsBBM1 resulted in somatic embryogenesis without the need for exogenous auxins. Genetic mutant analysis of OsBBM1 downstream targets, OsYUCCA6, OsYUCCA7 and OsYUCCA9, show that they are required for normal rice development including root and shoot development. Somatic embryogenic potential of OsYUCCA triple mutants was highly compromised despite the presence of exogenous auxin. Additionally, we show that somatic embryogenesis induction by exogenous auxin in rice requires functional BBM genes. Thus, OsBBM1 mediated cellular reprogramming and somatic embryogenesis likely involves increased localized auxin through direct upregulation of OsYUCCA genes. This study reveals mechanistic details of how somatic embryogenesis is established in differentiated tissues in rice, a monocot model and agronomically important cereal crop, with the potential utility to improve regeneration from tissue culture for recalcitrant plants in future.

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“…The previous studies showed that YUCCA gene members shared highly conserved motifs, namely, the FAD-binding motif (GxGPxGLA), the nicotinamide adenine dinucleotide phosphate (NADPH)-binding motif (GxGxxGME), GC motif (ERxxxxASL), and ATG-containing motif (DxxxxATG) [24], which might be the pivotal sites for the biological functions of YUCCA genes. Furthermore, some evidence suggested that the FAD-and NADPH-binding motif GxGxxG is central to YUCCA activity [32].…”

Section: Introductionmentioning

confidence: 99%

Genome-Wide Identification and Analysis on YUCCA Gene Family in Isatis indigotica Fort. and IiYUCCA6-1 Functional Exploration

Qin¹,

Wang²,

Zhang³

et al. 2020

IJMS

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Auxin is one of the most critical hormones in plants. YUCCA (Tryptophan aminotransferase of Arabidopsis (TAA)/YUCCA) enzymes catalyze the key rate-limiting step of the tryptophan-dependent auxin biosynthesis pathway, from IPA (Indole-3-pyruvateacid) to IAA (Indole-3-acetic acid). Here, 13 YUCCA family genes were identified from Isatis indigotica, which were divided into four categories, distributing randomly on chromosomes (2n = 14). The typical and conservative motifs, including the flavin adenine dinucleotide (FAD)-binding motif and flavin-containing monooxygenases (FMO)-identifying sequence, existed in the gene structures. IiYUCCA genes were expressed differently in different organs (roots, stems, leaves, buds, flowers, and siliques) and developmental periods (7, 21, 60, and 150 days after germination). Taking IiYUCCA6-1 as an example, the YUCCA genes functions were discussed. The results showed that IiYUCCA6-1 was sensitive to PEG (polyethylene glycol), cold, wounding, and NaCl treatments. The over-expressed tobacco plants exhibited high auxin performances, and some early auxin response genes (NbIAA8, NbIAA16, NbGH3.1, and NbGH3.6) were upregulated with increased IAA content. In the dark, the contents of total chlorophyll and hydrogen peroxide in the transgenic lines were significantly lower than in the control group, with NbSAG12 downregulated and some delayed leaf senescence characteristics, which delayed the senescence process to a certain extent. The findings provide comprehensive insight into the phylogenetic relationships, chromosomal distributions, and expression patterns and functions of the YUCCA gene family in I. indigotica.

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The Roles of Auxin Biosynthesis YUCCA Gene Family in Plants

Cited by 125 publications

References 164 publications

The “Green” FMOs: Diversity, Functionality and Application of Plant Flavoproteins

The “Green” FMOs: Diversity, Functionality and Application of Plant Flavoproteins

Rice embryogenic trigger BABY BOOM1 promotes somatic embryogenesis by upregulation of auxin biosynthesis genes

Genome-Wide Identification and Analysis on YUCCA Gene Family in Isatis indigotica Fort. and IiYUCCA6-1 Functional Exploration

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