The roles of 10-methacryloyloxydecyl dihydrogen phosphate and its calcium salt in preserving the adhesive–dentin hybrid layer

Jin, Xin; Han, Fei; Wang, Qi; Yuan, Xiaoqi; Zhou, Qiyue; Xie, Haifeng; L, Niu; Chen, Chen

doi:10.1016/j.dental.2022.06.007

Cited by 19 publications

(12 citation statements)

References 49 publications

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“…The different results found for dentin can be explained by the different compositions of the UAs analyzed-those with the functional monomer 10-MDP in their composition showed better results in terms of bond strength and stability over time due to the strong hydrophobicity of the hybrid layer formed (10-MDP and hydroxyapatite crystals). This layer protects against the hydrolytic degradation process, as demonstrated in the outputs of the study by Jin et al (2022). The authors concluded that 10-MDP forms a stable collagenphosphate complex with the collagen present in dentin, generating MDP-calcium salts that are deposited on the dentin collagen frame, which protects it from hydrolytic degradation.…”

Section: Discussionmentioning

confidence: 81%

Universal Adhesives: Evaluation of the Relationship between Bond Strength and Application Strategies—A Systematic Review and Meta-Analyses

et al. 2022

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Adhesive resins with guided application protocols have been developed with the main goal of reducing the number of clinical steps. Universal Adhesives (UA) can be applied with both Self-Etch (SE) or Etch-and-Rinse (ER) adhesion strategies. This review aims to evaluate the bond strength of UA, applied to dental tissues, by a systematic bibliometric review of in vitro studies. The research question, through the PICO model, aimed to assess the current knowledge of the immediate and long-term bond strength of UA, applied with a direct restorative technique. PubMed and ScienceDirect database searches focused on the bond resistance of UA applied with the ER and SE strategies. Studies assessing shear bond strength and microtensile bond strength, in both enamel and dentin, were included. From 1109 screened articles, 12 fulfilled the inclusion criteria. The bond strength of UA to enamel showed better results with the ER approach, while the adhesion strategy did not significantly affect the bond strength of UA to dentin. Evidence from in vitro studies has tended to suggest that the use of the SE adhesion approach seems to be a better choice to improve the bond strength to the dentin. The selective enamel etching is advisable when applied with the SE adhesion approach to optimize the UA bond strength to the enamel.

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Section: Discussionmentioning

confidence: 81%

Universal Adhesives: Evaluation of the Relationship between Bond Strength and Application Strategies—A Systematic Review and Meta-Analyses

et al. 2022

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“…As shown in molecular docking simulations (Table 2 and Fig. 8 ), and four dimers of TFs insert hydrophobic cavities along the collagen surface, covering the recognition sites of collagen surface enzymes to provide direct physical protection to the collagen 26 . In addition, the hydrophobic chains of TFs interact with the hydrophobic regions of collagen, This hydrophobic interaction may also help to exclude water molecules from the collagen surface in the aqueous medium, which in turn helps to protect dentin collagen from MMP 59 .…”

Section: Discussionmentioning

confidence: 95%

“…The interactions between MMP-2(PDB IDs:1QIB)/MMP-9 (PDB IDs: 2OW0) 25 , 26 and TFs were simulated using AutoDock 4.2 ( https://autodock.scripps.edu/)software 27 . The crystal structures of MMP-2 and MMP-9 were selected from the Protein Data Bank (PDB) database ( https://www1.rcsb.org/ ).…”

Section: Methodsmentioning

confidence: 99%

The roles of theaflavins in reducing dentin erosion

Guo

Yang

2023

Sci Rep

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This study aimed to evaluate the effect of theaflavins [TFs] on the process of dentin erosion and investigation the potential mechanism. For erosion kinetics of the dentin, 7 experimental groups (n = 5) treated with 10% ethanol [EtOH] (negative control) are erosion for 1, 2, 3, 4, 5, 6, and 7 d erosion cycles (4 cycles/d). For the effect of TFs on dentin erosion, 6 experimental groups (n = 5) were treated with 1% epigallocatechin gallate [EGCG], 1% chlorhexidine [CHX], 1%, 2%, 4%, and 8% TFs for the 30 s and then subjected to erosion cycles (4 cycles/d for 7 d). The erosive dentin wear (μm) and surface morphology were evaluated and compared by laser scanning confocal microscope and scanning electron microscopy. The matrix metalloproteinase inhibition effects of TFs were investigated using in situ zymography and molecular docking. TFs-treated collagen was investigated by ultimate microtensile strength, Fourier-transform infrared spectroscopy, and molecular docking. Data were analyzed by ANOVA, Tukey’s test (P < 0.05). The TFs-treated groups (7.56 ± 0.39, 5.29 ± 0.61, 3.28 ± 0.33, and 2.62 ± 0.99 μm for 1%, 2%, 4%, and 8% TFs) had significantly lower erosive dentin wear than the negative control group (11.23 ± 0.82 μm), and the effect was concentration-dependent at low concentrations (P < 0.05). TFs inhibit matrix metalloproteinase [MMP]. Moreover, TFs crosslink dentin collagen and cause hydrophilic changes in dentin collagen. TFs preserve organic matrix within the demineralized dentin by inhibiting MMP activity and simultaneously improving collagen’s resistance to enzymes, both of which contribute to preventing or slowing down the progression of dentin erosion.

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“…An effective bond can be formed between MDP acidic group and the oxide layer of zirconia. Several investigations have concluded that micromechanical pretreatment of zirconia with alumina particles (50 μm) and the use of an MDP‐based cement provide high bond strength to zirconia substrate 13,18,19 and to dentin by preserving the collagen within the hybrid layer 20 …”

Section: Introductionmentioning

confidence: 99%

“…Several investigations have concluded that micromechanical pretreatment of zirconia with alumina particles (50 μm) and the use of an MDP-based cement provide high bond strength to zirconia substrate 13,18,19 and to dentin by preserving the collagen within the hybrid layer. 20 The majority of the previous studies evaluating adhesion to zirconia were in vitro based using macroshear, macrotensile or microtensile testing. 18,21 However, their results are difficult to be generalised clinically due to the complex oral environment.…”

mentioning

confidence: 99%

Clinical evaluation of zirconia crowns cemented with two different resin cements: A retrospective study

Aziz,

El‐Mowafy

2023

J of Oral Rehabilitation

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BackgroundSelf‐adhesive resin cement has been used extensively with zirconia crowns. Several in vitro studies showed that adhesive resin cementation may increase zirconia crowns' retention and their fatigue resistance.ObjectivesThis retrospective study aimed to evaluate the clinical performance, survival and success rates and complications encountered with zirconia crowns cemented with two different self‐adhesive resin cements.MethodsA total of 112 patients who received 176 monolithic zirconia crowns were evaluated. Crowns were cemented with RelyX Unicem 2 (n = 74) and Panavia SA (n = 102) self‐adhesive resin cements. Clinical assessments of the crowns and supporting periodontal structures were performed following the modified California Dental Association (CDA) criteria. Intraoral photographs and periapical and bitewing radiographs were obtained for further assessment by two evaluators. Descriptive statistics, McNemar, t‐test, log rank (Mantel‐Cox) tests and Kaplan–Meier survival analyses were performed (a = .05).ResultsThe 5‐year survival and success rates were 100% and 96.4%, respectively. The complications encountered were recurrent caries (2.2%) and the need for endodontic treatment (0.5%). No technical complications, such as fracture or loss of retention, were observed. The type of cement and patient‐related factors did not influence the survival and success rates of the crowns.ConclusionsSurvival rate of zirconia crowns cemented with two different self‐adhesive resin cements was 100% after 5 years.

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The roles of 10-methacryloyloxydecyl dihydrogen phosphate and its calcium salt in preserving the adhesive–dentin hybrid layer

Cited by 19 publications

References 49 publications

Universal Adhesives: Evaluation of the Relationship between Bond Strength and Application Strategies—A Systematic Review and Meta-Analyses

Universal Adhesives: Evaluation of the Relationship between Bond Strength and Application Strategies—A Systematic Review and Meta-Analyses

The roles of theaflavins in reducing dentin erosion

Clinical evaluation of zirconia crowns cemented with two different resin cements: A retrospective study

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