The Role of β3-Adrenergic Receptors in Cold-Induced Beige Adipocyte Production in Pigs
Shuo Yang,
Hong Ma,
Liang Wang
et al.
Abstract:After exposure to cold stress, animals enhance the production of beige adipocytes and expedite thermogenesis, leading to improved metabolic health. Although brown adipose tissue in rodents is primarily induced by β3-adrenergic receptor (ADRB3) stimulation, the activation of major β-adrenergic receptors (ADRBs) in pigs has been a topic of debate. To address this, we developed overexpression vectors for ADRB1, ADRB2, and ADRB3 and silenced the expression of these receptors to observe their effects on the adipoge… Show more
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