The Role of Zinc in Mood Disorders

Piao, Meihua; Cong, Xiangyu; Lu, Yuanxu; Feng, Chong; Ge, Pengfei

doi:10.4172/neuropsychiatry.1000225

Cited by 7 publications

(8 citation statements)

References 116 publications

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“…Zinc deficiency results from low food intake and affects growth, immune defense, cognitive function, and bone health. Therefore, zinc deficiency, similar to hypomagnesemia, can increase stress and reduce the quality of life by causing palpitations, dry skin, hair loss, depression, visual disturbance, hearing loss, and loss of taste and smell [35,36]. Our data suggests that beef containing appropriate mineral amounts could offer potential health benefits.…”

Section: Sensory and Mineral Evaluationmentioning

confidence: 83%

Nuclear magnetic resonance-based metabolomics analysis and characteristics of beef in different fattening periods

Jeong¹,

Baek²,

Ji³

et al. 2020

J Anim Sci Technol

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Beef quality is influenced by the fattening period. Therefore, meat metabolomics profiles from the different fattening periods (e.g., short-term vs. long-term) were analyzed for identify potential indicators using nuclear magnetic resonance. Additionally, blood, free fatty acid, sensory, and mineral compositions in Korean steers were determined. Blood, free fatty acid, and mineral concentrations showed significant differences between short-term and long-term groups that were fed different diets. However, there were no sensory differences in the two fattening groups. Additionally, the metabolic profiles of meats were clearly separated based on multivariate orthogonal partial least square discriminant analysis. Six metabolites of variable importance in the projection plot were identified and showed high sensitivity as candidate markers for meat characteristics. In particular, lactate, carnosine, and creatine could be directly linked to scientific indicators of the fattening stage (31 vs. 28 mo) of meat. Our findings suggest that the metabolomics approach could be a powerful method for the detection of novel signatures underlying the managing period of beef.

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Section: Sensory and Mineral Evaluationmentioning

confidence: 83%

Nuclear magnetic resonance-based metabolomics analysis and characteristics of beef in different fattening periods

Jeong¹,

Baek²,

Ji³

et al. 2020

J Anim Sci Technol

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“…A study by Kennedy reported vitamin B6 in the involvement of neurotransmitter pathways; it is a cofactor in the production of serotonin from tryptophan, and that low plasma level of B6 has been associated with depression (Kennedy 2016). Vitamin B-12 has neurological function, and it is also a cofactor in the production of neurotransmitters (Rechenberg and Humphries 2013;Ford et al 2018;Meihua et al 2017). Other functions of B12 include forming red blood cells and maintaining nervous system.…”

Section: Nutritional Science Brain and Mental Healthmentioning

confidence: 99%

“…Other functions of B12 include forming red blood cells and maintaining nervous system. Zinc, is an essential nutritional element which plays many key roles including enzyme catalysis, cell signaling, DNA replication, and transcription and therefore is essential for neural development in learning and memory function as well as mood stability (Meihua et al 2017). Zinc has also been used as an anti-depressant (Ranjbar et al 2013).…”

Section: Nutritional Science Brain and Mental Healthmentioning

confidence: 99%

Nutritional Deficiencies and Maternal Depression: Associations and Interventions in Lower and Middle-Income Countries: a Systematic Review of Literature

et al. 2021

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Background Nutrition deficiencies are common among pregnant and lactating women in middle- and low-income countries. At the same time, maternal mental disorders, mainly depression is highly prevalent during this period suggesting some connection between the two. The objective of this review is to determine the associations between nutritional deficiencies and maternal depression and identify the role of diet in depression to facilitate further research. Methods A literature search included PubMed databases and Google Scholar search engine published from June 2008 to June 2019 and published in English. Medical subject heading terms was used to identify all relevant studies. All titles and abstracts identified by the search were screened then reviewed the full-text articles which were potentially eligible for inclusion. Results The original search identified 1250 articles but with cascaded elimination, based on quality. Twenty five met the inclusion criteria, of which 13 were cross-sectional, eight were prospective cohort study, and four were intervention studies. Most (95%) of these studies reported positive associations between nutrition deficiencies, poor diet, and maternal depression; thus, only 5% did not show associations between nutrition and depression. Conclusion Our review findings suggest that nutritional interventions are some of the most promising intercessions for mental health illnesses. Not all studies consistently associate poor diet quality with poor maternal and offspring mental health outcomes, and the majority of those that show are cross-sectional. Considering that most of these associations are cross-sectional, studies devoid of exposing causal relationship; thus, longitudinal studies are needed to confirm the associations towards sufficing as a window of opportunity for reducing the risk of mental disorders in mothers and offspring alike.

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“…In particular, zinc deficiency can trigger aggressive and antisocialdis position (Piao, Cong, Lu, Feng, Ge , 2017), behavior (attention span, temperament, recreation activities), rough and fine mobility as well as social skills. (Cogia & Sachdev, 2012).…”

Section: Zincmentioning

confidence: 99%

The Role of Nutrients in Child’s Brain Development

Karavida¹,

Tympa²,

Charissi³

2019

JEHD

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Early childhood is a basic stage for the child's later life. During this period the brain development and the foundations for cognitive development and social-emotional skills, is laid. Nutrition plays a key role in optimal brain function. When a child is adequately fed, the basis for smooth brain function is created. Nutritional deficiencies may affect the child's cognitive skills and behavior. Since rapid brain development occurs during the early years, this period may be particularly sensitive to deficiencies in the diet. Modern data shows that diet seems to be one of the most important growth and maturation factors in the brain both in infancy and childhood. In particular, fatty acids play a central role in brain tissue, iron deficiency causes disturbances in attention, memory and behavior, and is closely linked to lower cognitive indices. Long-term studies have shown that children with iron deficiency have lower school performance. In addition, zinc, as well as iodine and vitamins D and B12 deficiencies are likely to adversely affect brain function and memory. An inadequate diet usually causes multiple deficiencies of micronutrients with short-term and long-term effects on the functioning of the child's brain.

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The Role of Zinc in Mood Disorders

Cited by 7 publications

References 116 publications

Nuclear magnetic resonance-based metabolomics analysis and characteristics of beef in different fattening periods

Nuclear magnetic resonance-based metabolomics analysis and characteristics of beef in different fattening periods

Nutritional Deficiencies and Maternal Depression: Associations and Interventions in Lower and Middle-Income Countries: a Systematic Review of Literature

The Role of Nutrients in Child’s Brain Development

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