The Role of Vaccination Interventions to Promote HPV Vaccine Uptake Rates in a College-Aged Population: a Systematic Review

Abstract

This systematic review provided synthesized evidence regarding the effectiveness of the interventions promoting the human papillomavirus (HPV) vaccination in college-aged population. The HPV infection is the most prevailing sexually transmitted disease. Despite the availability and effectiveness of the 9-Valent HPV vaccine, the vaccine coverage among young adults remained low. In witness to the increasing burden of HPV-related infections and cancers, research focused on the vaccination interventions should be conducted to determine the effectiveness of the vaccination strategy and address the gap. The search was conducted through PubMed, Cochrane, and CINAL. Studies were included if they (1) included vaccination programs, (2) target population was young adults aged 17–26, (3) examined factors associated with the intervention effectiveness, (4) were published in English, and (5) were published between February 2010 and February 2020. HPV-related knowledge and intentions toward HPV vaccination were all reported increased after the intervention. Increased HPV vaccination intentions were found associated with the increased vaccine initiation and completion. Among bisexual or homosexual individuals, females were found more likely to complete the HPV dose 2 and 3. The review findings suggested using vaccination interventions incorporated with educational components to promote vaccine uptake among young adults. Supportive interventions tailored to different populations and settings are crucial to address the suboptimal HPV-related knowledge and vaccination status among the young beneficiaries.

HPV vaccine awareness, knowledge and information sources among youth in Switzerland: a mixed methods study

“…This confirms results from previous reports. 11 [15][16][17] In our study, we only saw a trend towards a small difference in HPV vaccine knowledge between the younger and older age groups. Other studies, however, found a higher knowledge score in older compared with younger participants.…”

Using Machine Learning to Compare Provaccine and Antivaccine Discourse Among the Public on Social Media: Algorithm Development Study

“…Exposure to antivaccine content on social media has been associated with delays in and refusal of vaccination [3]. While the development of tailored messages (eg, text messages) has increased immunization rates [10], public provaccine campaigns via social media have yielded limited success, as shown in several systematic reviews of interventions for various vaccines [4,[11][12][13][14][15][16][17][18][19]. Given that there is a methodological barrier to assessing the impact of public campaigns on regional immunization rates, the current literature has not yet fully explicated how the antivaccine movement continues to engage and persuade the public to deny immunization despite provaccine advocates' counteracting efforts.…”

Do social media campaigns foster vaccination adherence? A systematic review of prior intervention-based campaigns on social media

“…Even before the COVID-19 vaccination program started in the US, interventions to increase immunization rates were a focus of systematic reviews to counteract declining immunization rates ( Asare et al, 2021 , Crocker-Buque et al, 2017 ; Falcone, 2019; Jarrett et al, 2015 , Lott et al, 2020 , Niccolai and Hansen, 2015 , Nour, 2019 , Odone et al, 2015 , Ortiz et al, 2019 , Ou and Youngstedt, 2020 , Smulian et al, 2016 ). However, most of these reviews focused on narrow regions or clinician–patient communication, and thus their findings are not directly applicable to social media–based intervention campaigns disseminated to broader audiences.…”