The role of ultrasound-guided needle biopsy in the diagnosis of soft-tissue tumors

Battaglia, Milva; Pollastri, Paola; Ferraro, A.; Betoni, F.; Bacci, Gaetano; Galletti, Stefano

doi:10.1016/j.jus.2007.03.001

Cited by 6 publications

(7 citation statements)

References 7 publications

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“…Our success rate was slightly higher than that reported by Battaglia et al. 20 In their study, sufficient material for histologic diagnosis was collected in 148 of 164 cases (90%). Our better performance was mainly due to the gauge of our needles (14G) being larger than that of their needles (15–18G).…”

Section: Discussioncontrasting

confidence: 63%

Diagnostic yield of percutaneous core needle biopsy in suspected soft tissue lesions of extremities

Zhao

et al. 2019

J Int Med Res

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Objective This retrospective study was performed to investigate the diagnostic yield of percutaneous core needle biopsy (CNB) for suspected soft tissue lesions of the extremities. Methods The medical records of 139 consecutive patients who underwent percutaneous CNB for suspected soft tissue lesions of the extremities from January 2014 to December 2016 at a single institution were reviewed. The pathologic findings or clinical follow-ups were used to evaluate the performance of CNB. Alterations in the treatment regimen from pre- to post-biopsy were also analyzed. Complications, when present, were documented. Results In total, 141 biopsy procedures were performed in 139 patients. In total, 136 (96%) biopsies were successful, among which 5 were false-negative and 131 were diagnosed accurately. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of CNB in the differentiation of malignant from benign lesions were 94%, 100%, 96%, 100%, and 90%, respectively. The treatment regimen was altered based on the biopsy findings in 25 cases. Two patients developed mild nerve injury but fully recovered during follow-up. Conclusions CNB is effective and safe, with high sensitivity, specificity, and accuracy for the diagnosis of soft tissue lesions, especially for differentiating malignant from benign lesions.

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Section: Discussioncontrasting

confidence: 63%

Diagnostic yield of percutaneous core needle biopsy in suspected soft tissue lesions of extremities

Zhao

et al. 2019

J Int Med Res

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“…Bony PCBs are usually fluoroscopy-guided and performed with a trocar of 11 Gauge, with a percentage of diagnostic results ranging between 75% to 98% [14,17,18,22,27,[31][32][33]41]. Instead, PCBs for soft tissue lesions are generally ultrasound-guided and performed with a 14-gauge tru-cut needle, with a diagnostic result reported in literature ranging from 83% to 96% [12,13,19,20,29,32,33,[35][36][37][38][39][40][41][42][43][44]. The incidence of non-diagnostic PCB is higher in soft tissue than in bone lesions, probably due to the high presence of necrotic areas that could make histological interpretation more difficult [34,43,44].…”

Section: Discussionmentioning

confidence: 99%

“…Instead, PCBs for soft tissue lesions are generally ultrasound-guided and performed with a 14-gauge tru-cut needle, with a diagnostic result reported in literature ranging from 83% to 96% [12,13,19,20,29,32,33,[35][36][37][38][39][40][41][42][43][44]. The incidence of non-diagnostic PCB is higher in soft tissue than in bone lesions, probably due to the high presence of necrotic areas that could make histological interpretation more difficult [34,43,44]. In our series, adequate material for diagnosis was obtained more frequently in bone (97%, 366/376), than in soft tissue (94%, 304/322).…”

Section: Discussionmentioning

confidence: 99%

“…Repeating another PCB led to diagnosis in 99% and 98% of cases, respectively in bone and soft tissue lesions: non-diagnostic results could be defined as sampling error, due to necrotic, fibrous, or haemorrhagic tissue. In order to reduce non-diagnostic procedures, multiple samples from different areas of the tumor should be done using larger needles [44].…”

Section: Discussionmentioning

confidence: 99%

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Image-Guided Percutaneous Biopsy for the Diagnosis of Musculoskeletal Tumors: An Analysis of 698 Cases and a Literature Review

Trovarelli¹,

Castaneda-Martinez²,

Pala³

et al. 2020

JSCR

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Purpose: Incisional biopsy is still used to obtain material for a straightforward histological diagnosis in musculoskeletal lesions. The aim of our study was to evaluate 1) the percentage of diagnostic procedures, 2) diagnostic accuracy, and 3) the incidence of complications after imaging-guided percutaneous biopsy (PCB). Case Series: This is a retrospective analysis of imaging-guided PCB performed between January 2016 and September 2019 by fluoroscopy in bone lesions or under ultrasound-guidance in soft tissue lesions. Specimens were classified as diagnostic or non-diagnostic according to the pathologist’s report; diagnostic accuracy was determined by comparing histopathological results from biopsy and tumor resection. PCB was diagnostic in 94% and 97% of cases, with a diagnostic accuracy for detecting tumor disease in soft tissue and bone lesions of 98% and 100%, respectively. No complications were observed. Discussion: The PCB is safe, minimally invasive, and cost-effective; thus, it should be the gold standard for the diagnosis of musculoskeletal lesions.

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“…12 It can distinguish malignant versus benign musculoskeletal tumors 13 and guide their needle biopsy. 14 Use of intraoperative US (IOUS) in cancers such as breast cancer, 15 liver cancer, 16 and tongue cancer 17 has been well established. 18 Krekel et al 15 reported that IOUS-guided breast cancer excision achieved a significantly clearer margin than did palpation-guided surgery, which reduced the need for re-excision, mastectomy, radiotherapy, and unnecessary resection of healthy breast tissue.…”

Section: Introductionmentioning

confidence: 99%

Intraoperative ultrasonography‐guided surgery for malignant soft tissue tumor

Takeuchi

Yamamoto

Hayashi

et al. 2020

Journal of Surgical Oncology

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Background and Objectives: A clear surgical margin is crucial for preventing the recurrence of soft tissue sarcomas (STSs). Recognizing the tumor border is difficult when the STS is impalpable or ill-defined. Ultrasonography (US) is a widely used diagnostic device that can visualize certain tumors intraoperatively. However, its usefulness for intraoperatively assessing STSs is unclear and was investigated here. Methods: Our study comprised 19 patients with STSs that were impalpable, illdefined, or beneath the fascia. All patients underwent intraoperative US (IOUS), with follow-up times ranging from 5 to 103 months (mean, 49 months). Results: The mean age of the study participants was 56 years (range, 25-83 months). The most common histological diagnosis was undifferentiated pleomorphic sarcoma (UPS) (nine patients). The mean tumor size was 51 mm (range, 7-126 mm). According to the residual tumor classification, 18 tumors were microscopically negative (R0), including seven close to the fascia, and one was microscopically positive (R1). Local recurrence occurred in two cases (both classified as R0). The recurrence-free survival rate was 88.9% in 5 years. Conclusions: IOUS-guided surgery is useful for visualizing STSs. Using this technique, STSs can be precisely localized, evaluated, and excised.

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The role of ultrasound-guided needle biopsy in the diagnosis of soft-tissue tumors

Cited by 6 publications

References 7 publications

Diagnostic yield of percutaneous core needle biopsy in suspected soft tissue lesions of extremities

Diagnostic yield of percutaneous core needle biopsy in suspected soft tissue lesions of extremities

Image-Guided Percutaneous Biopsy for the Diagnosis of Musculoskeletal Tumors: An Analysis of 698 Cases and a Literature Review

Intraoperative ultrasonography‐guided surgery for malignant soft tissue tumor

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