The Role of Tibial Plateau Angle in Canine Cruciate Ligament Rupture—A Review of the Literature

Todorović, Anastasija; Macanović, Mirjana Lazarević; Mitrovic, Milan; Krstić, Nikola; Bree, Henri J. J. van; Gielen, Ingrid

doi:10.1055/s-0042-1750316

Cited by 6 publications

(2 citation statements)

References 64 publications

(160 reference statements)

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“…At present, the most popular surgical technique is the tibial plateau leveling osteotomy (TPLO). The leveling procedure brings the knee joint in a more flexed position, which results in a dynamic stabilization ( 91 ). Without weight bearing and active stabilization through the quadriceps mechanism, the knee joint still shows a positive drawer sign.…”

Section: Animals As Translational Research Modelsmentioning

confidence: 99%

Osteoarthritis, adipokines and the translational research potential in small animal patients

Theyse,

Mazur

2024

Front. Vet. Sci.

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Osteoartritis (OA) is a debilitating disease affecting both humans and animals. In the early stages, OA is characterized by damage to the extracellular matrix (ECM) and apoptosis and depletion of chondrocytes. OA progression is characterized by hyaline cartilage loss, chondrophyte and osteophyte formation, thickening of the joint capsule and function loss in the later stages. As the regenerative potential of cartilage is very limited and osteoarthritic changes are irreversible, prevention of OA, modulation of existing osteoarthritic joint inflammation, reducing joint pain and supporting joint function are the only options. Progression of OA and pain may necessitate surgical intervention with joint replacement or arthrodesis as end-stage procedures. In human medicine, the role of adipokines in the development and progression of OA has received increasing interest. At present, the known adipokines include leptin, adiponectin, visfatin, resistin, progranulin, chemerin, lipocalin-2, vaspin, omentin-1 and nesfatin. Adipokines have been demonstrated to play a pivotal role in joint homeostasis by modulating anabolic and catabolic balance, autophagy, apoptosis and inflammatory responses. In small animals, in terms of dogs and cats, naturally occurring OA has been clearly demonstrated as a clinical problem. Similar to humans, the etiology of OA is multifactorial and has not been fully elucidated. Humans, dogs and cats share many joint related degenerative diseases leading to OA. In this review, joint homeostasis, OA, adipokines and the most common joint diseases in small animals leading to naturally occurring OA and their relation with adipokines are discussed. The purpose of this review is highlighting the translational potential of OA and adipokines research in small animal patients.

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Section: Animals As Translational Research Modelsmentioning

confidence: 99%

Osteoarthritis, adipokines and the translational research potential in small animal patients

Theyse,

Mazur

2024

Front. Vet. Sci.

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“…[1][2][3][4][5][6] This is achieved by reducing the tibial plateau angle (TPA) to between 5 and 6.5 degrees. 1,2,[7][8][9][10][11] Several complications have been reported following TPLO, including implant failure, infection, patellar fracture, tibial tuberosity fracture, patellar desmitis, tibial fracture, meniscal tear, and rockback. [12][13][14][15][16] Rock-back is a reported complication following TPLO, whereby TPA increases between the index surgery and osteotomy union.…”

Section: Introductionmentioning

confidence: 99%

Effect of Plate Inclination and Osteotomy Positioning on Rock-back following Tibial Plateau Levelling Osteotomy in Dogs

Mclean,

Foo,

Toh

et al. 2024

Vet Comp Orthop Traumatol

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Objective Rock-back is a reported complication following tibial plateau levelling osteotomy (TPLO), whereby tibial plateau angle (TPA) increases postoperatively. The mechanism of rock-back is not fully understood, although a recent ex vivo investigation demonstrated that osteotomy exit cut angle (ECA) and inclination of the plate in the sagittal plane might be risk factors. The purpose of this study was to explore these relationships in a clinical dog population. We hypothesized that dogs with rock-back would have a higher degree of plate inclination and downward ECA compared with those without rock-back. Materials and Methods Medical records and radiographs of dogs that underwent TPLO between January 2021 and January 2022 were retrospectively reviewed. TPA was recorded preoperatively, postoperatively, and at follow-up. Plate inclination, ECA, and descriptive data were collected. Observers measuring TPA were blinded to other variables. Rock-back was defined as a change in TPA ≥ 2. Results Ninety-five TPLO procedures met the inclusion criteria (n = 87 dogs). Rock-back was identified in 21% of TPLOs (n = 20/95). The mean increase in TPA in the rock-back group was 3.2 ± 2.6. Plate inclination and ECA were not correlated with the presence of rock-back. Descriptive variables did not have a significant correlation with rock-back. Conclusion Plate inclination and ECA did not have a relationship with rock-back when defined as a postoperative TPA change ≥2 degrees, in this clinical retrospective study.

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Reported accuracy of cranial closing wedge ostectomy variants for management of canine cranial cruciate ligament insufficiency: A systematic review and meta-analysis

Miles

Nielsen

2023

The Veterinary Journal

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The Role of Tibial Plateau Angle in Canine Cruciate Ligament Rupture—A Review of the Literature

Cited by 6 publications

References 64 publications

Osteoarthritis, adipokines and the translational research potential in small animal patients

Osteoarthritis, adipokines and the translational research potential in small animal patients

Effect of Plate Inclination and Osteotomy Positioning on Rock-back following Tibial Plateau Levelling Osteotomy in Dogs

Reported accuracy of cranial closing wedge ostectomy variants for management of canine cranial cruciate ligament insufficiency: A systematic review and meta-analysis

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