The role of thrombomodulin in modulating ITGB3 expression and its implications for triple‐negative breast cancer progression
Yu‐Jia Chang,
G. M. Shazzad Hossain Prince,
Po‐Li Wei
et al.
Abstract:Triple‐negative breast cancer (TNBC) is the most aggressive subtype of breast cancer (BC) compared to other BC subtypes in clinical settings. Currently, there are no effective therapeutic strategies for TNBC treatment. Therefore, there is an urgent need to identify suitable biomarkers or therapeutic targets for TNBC patients. Thrombomodulin (TM) plays a role in cancer progression and metastasis in many different cancers. However, the role of TM in TNBC is not yet fully understood. First, silenced‐TM in MDA‐MB‐… Show more
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