Abstract:Our results suggest that retrograde colonic enema was not inferior to Malone antegrade continence enema on fecal continence. We recommend considering retrograde colonic enema prior to introduction of Malone antegrade continence enema in children with spina bifida.
“…4 The initiating event for the deterioration of the patient's fecal control was the FEC 100 chemotherapy. The FEC 100 regimen has been shown to be an efficacious adjuvant treatment for breast cancer.…”
Survival to adulthood in spina bifida has greatly increased with the advent of modern therapies. With this prolonging of life expectancy, patients are exposed to the risk of adult onset malignancies and the complications of subsequent treatment. We present the case of a 66-year-old woman born with a terminal lipomyelomeningocele, presenting with new fecal incontinence and a desire to undivert her ileal conduit. The deterioration was attributed to chemotherapy for breast cancer. We highlight the urologic challenges of breast cancer management in the neurogenic bowel population, as well as the utility of an adult spina bifida clinic. To the best of our knowledge, this is the first case report of a spina bifida patient presenting with fecal and urinary complications from breast cancer chemotherapy.
“…4 The initiating event for the deterioration of the patient's fecal control was the FEC 100 chemotherapy. The FEC 100 regimen has been shown to be an efficacious adjuvant treatment for breast cancer.…”
Survival to adulthood in spina bifida has greatly increased with the advent of modern therapies. With this prolonging of life expectancy, patients are exposed to the risk of adult onset malignancies and the complications of subsequent treatment. We present the case of a 66-year-old woman born with a terminal lipomyelomeningocele, presenting with new fecal incontinence and a desire to undivert her ileal conduit. The deterioration was attributed to chemotherapy for breast cancer. We highlight the urologic challenges of breast cancer management in the neurogenic bowel population, as well as the utility of an adult spina bifida clinic. To the best of our knowledge, this is the first case report of a spina bifida patient presenting with fecal and urinary complications from breast cancer chemotherapy.
“…A subgroup of up to 10% of patients with chronic constipation does not sufficiently respond to dietary changes, oral laxatives, rectal enemas, or retrograde lavage . While retrograde colon lavage can be efficacious, it is time‐consuming and often large volumes are needed, resulting in considerable patient discomfort. When all conservative measures fail, surgical treatments such as appendicostomy, ileostomy with colonic exclusion, or segmental or total colectomy are considered .…”
PEC offers a technically easily feasible and safe treatment option for patients with chronic constipation not responding to conventional therapy. Long-term efficacy of PEC in our patients is 50%.
“…[12][13][14][15][16] In recent years, transanal irrigation (TAI) has become a popular option in the management of NBD due to its successful results and acceptable safety profile. [17][18][19][20][21][22][23] TAI has been suggested as a first-line therapy for children with neuropathic bowel dysfunction who do not respond to conservative medical therapy. 9 Moreover, TAI constitutes an integral part of the total endoscopic and anal irrigation management (TEAM) approach in children with noncompliant NB.…”
Section: Introductionmentioning
confidence: 99%
“…Matsuno and colleagues retrospectively compared 25 patients with spina bifida and fecal incontinence using either TAI or MACE. 23 They found no difference in the achievement of fecal continence between the 2 groups and concluded that TAI is not inferior to MACE. Our prospective results support their recommendation in considering TAI prior to the introduction of MACE in children with spina bifida.…”
mentioning
confidence: 96%
“…9,[17][18][19][20][21][22][23] TAI was associated with an excellent safety margin, and the reported complications were mostly minor and related to catheter manipulation (Table 2). [17][18][19][20][21] Forty-five pediatric patients using TAI were presented in the European Society for Pediatric Urology Annual Meeting in 2010.…”
Cite as: Can Urol Assoc J 2014;8(1-2):e12-5. http://dx.doi.org/10.5489/cuaj.1263 Published online January 14, 2014.
AbstractIntroduction: We evaluate the efficacy of the Peristeen (Coloplast A/S, Kokkedal, Denmark) transanal irrigation (TAI) system, as a stool cleansing mechanism, to gain stool continence in children who need reconstructive bladder surgery and have fecal incontinence. Methods: We prospectively evaluated children with neuropathic bladder and bowel dysfunction who were intended for reconstructive bladder surgery and the Malone antegrade continence enema (MACE) procedure. All patients were started on the Peristeen TAI system at least 3 months before surgery to assess their response. Each patient's bowel function, frequency of using the system, satisfaction (and that of their parents) and diaper independency were evaluated before and after reconstructive surgery. Results: We included 18 patients (11 female, 7 male) who were evaluated from April 2006 to the present. The mean age of the group was 7.6 years (range: 4-15). Fifteen patients (83.3%) showed complete dryness from stools. Of the 15 patients, 8 (53.3%) were able to be diaper-free, while 6 continued wearing diapers due to fear of soiling and 1 due to urinary incontinence. The patients underwent reconstructive bladder surgery and continued to use the Peristeen TAI system with the same results postoperatively. The main limitation of this study is the small number of patients included, although this is a very specific patient group. Conclusion: Our initial results suggest that the Peristeen TAI system is a successful conservative substitute for the MACE procedure in children who require reconstructive bladder surgery.
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