The role of the pyridoxine (vitamin B6) biosynthesis enzyme PDX1 in ultraviolet-B radiation responses in plants

Ristilä, Mikael; Strid, Hilja; Eriksson, Leif A.; Strid, Åke; Sävenstrand, Helena

doi:10.1016/j.plaphy.2011.01.003

Cited by 38 publications

(34 citation statements)

References 37 publications

(79 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Paralleling the stress induction of Arabidopsis PDX genes ( Fig. 5; Supplemental Table S2), PDX1.3 protein accumulated and the total B 6 level increased by 60% in response to UV-B exposure (Ristilä et al, 2011); total B 6 also increased by 60% in response to heat stress (Moccand et al, 2014). Levels of pyridoxal 59-phosphate and free pyridoxal or pyridoxine likewise increased by about 2-fold in tobacco exposed to chilling, UV radiation, osmotic stress, oxidative stress, or drought (Huang et al, 2013).…”

Section: Vitamin Bmentioning

confidence: 78%

Does Abiotic Stress Cause Functional B Vitamin Deficiency in Plants?

et al. 2016

View full text Add to dashboard Cite

B vitamins are the precursors of essential metabolic cofactors but are prone to destruction under stress conditions. It is therefore a priori reasonable that stressed plants suffer B vitamin deficiencies and that certain stress symptoms are metabolic knock-on effects of these deficiencies. Given the logic of these arguments, and the existence of data to support them, it is a shock to realize that the roles of B vitamins in plant abiotic stress have had minimal attention in the literature (100-fold less than hormones) and continue to be overlooked. In this article, we therefore aim to explain the connections among B vitamins, enzyme cofactors, and stress conditions in plants. We first outline the chemistry and biochemistry of B vitamins and explore the concept of vitamin deficiency with the help of information from mammals. We then summarize classical and recent evidence for stress-induced vitamin deficiencies and for plant responses that counter these deficiencies. Lastly, we consider potential implications for agriculture.

show abstract

Section: Vitamin Bmentioning

confidence: 78%

Does Abiotic Stress Cause Functional B Vitamin Deficiency in Plants?

et al. 2016

View full text Add to dashboard Cite

show abstract

“…This also suggests a potential for regulation of the ROS network that is beyond circadian regulation of rhythmic ROS genes. PYRIDOXINE BIOSYNTHESIS 1 (PDX1) encodes an enzyme involved in production of the ROS quencher pyridoxine that increases in levels upon UV-B irradiation (28). Notably, the expression of PDX1 is elevated in cca1-1/lhy-11 (Fig.…”

Section: Cca1 Regulates the Coordinated Transcription Of Ros Genes Inmentioning

confidence: 99%

CIRCADIAN CLOCK-ASSOCIATED 1 regulates ROS homeostasis and oxidative stress responses

Lai

Doherty

Mueller‐Roeber

et al. 2012

Proc. Natl. Acad. Sci. U.S.A.

313

306

View full text Add to dashboard Cite

Organisms have evolved endogenous biological clocks as internal timekeepers to coordinate metabolic processes with the external environment. Here, we seek to understand the mechanism of synchrony between the oscillator and products of metabolism known as Reactive Oxygen Species (ROS) in Arabidopsis thaliana. ROS-responsive genes exhibit a time-of-day-specific phase of expression under diurnal and circadian conditions, implying a role of the circadian clock in transcriptional regulation of these genes. Hydrogen peroxide production and scavenging also display time-ofday phases. Mutations in the core-clock regulator, CIRCADIAN CLOCK ASSOCIATED 1 (CCA1), affect the transcriptional regulation of ROSresponsive genes, ROS homeostasis, and tolerance to oxidative stress. Mis-expression of EARLY FLOWERING 3, LUX ARRHYTHMO, and TIMING OF CAB EXPRESSION 1 affect ROS production and transcription, indicating a global effect of the clock on the ROS network. We propose CCA1 as a master regulator of ROS homeostasis through association with the Evening Element in promoters of ROS genes in vivo to coordinate time-dependent responses to oxidative stress. We also find that ROS functions as an input signal that affects the transcriptional output of the clock, revealing an important link between ROS signaling and circadian output. Temporal coordination of ROS signaling by CCA1 and the reciprocal control of circadian output by ROS reveal a mechanistic link that allows plants to master oxidative stress responses.redox homeostasis | transcriptional coordination

show abstract

“…Moreover, the effect of UV-B on pathogen resistance was found to be mediated by UVR8 (Demkura and Ballare 2012). A role for UVR8 remains to be established in a number of other UV-B responses in Arabidopsis, including stomata regulation (Eisinger et al 2003), phototropism (Eisinger et al 2003, Shinkle et al 2004, dynamics of phytohormones under UV-B (Savenstrand et al 2004, Hectors et al 2012, vitamin B6 biosynthesis (Brosche et al 2002, Ristilä et al 2011, Morales et al 2013) and alterations in secondary metabolism (Jansen et al 2008, Kusano et al 2011. A number of further UVR8-mediated responses can be deduced from UV-B-induced and UVR8-dependent gene expression changes (Brosche et al 2002, Ulm et al 2004, Brown et al 2005, Oravecz et al 2006, Hectors et al 2007, Zhou et al 2007, Favory et al 2009, Morales et al 2013) but these remain to be validated.…”

Section: Uvr8-mediated Physiological Responsesmentioning

confidence: 99%

The UVR8 UV-B Photoreceptor: Perception, Signaling and Response

Tilbrook

Arongaus

Binkert

et al. 2013

The Arabidopsis Book

224

187

View full text Add to dashboard Cite

Ultraviolet-B radiation (UV-B)is an intrinsic part of sunlight that is accompanied by significant biological effects. Plants are able to perceive UV-B using the UV-B photoreceptor UVR8 which is linked to a specific molecular signaling pathway and leads to UV-B acclimation. Herein we review the biological process in plants from initial UV-B perception and signal transduction through to the known UV-B responses that promote survival in sunlight. The UVR8 UV-B photoreceptor exists as a homodimer that instantly monomerises upon UV-B absorption via specific intrinsic tryptophans which act as UV-B chromophores. The UVR8 monomer interacts with COP1, an E3 ubiquitin ligase, initiating a molecular signaling pathway that leads to gene expression changes. This signaling output leads to UVR8-dependent responses including UV-B-induced photomorphogenesis and the accumulation of UV-B-absorbing flavonols. Negative feedback regulation of the pathway is provided by the WD40-repeat proteins RUP1 and RUP2, which facilitate UVR8 redimerization, disrupting the UVR8-COP1 interaction. Despite rapid advancements in the field of recent years, further components of UVR8 UV-B signaling are constantly emerging, and the precise interplay of these and the established players UVR8, COP1, RUP1, RUP2 and HY5 needs to be defined. UVR8 UV-B signaling represents our further understanding of how plants are able to sense their light environment and adjust their growth accordingly.

show abstract

The role of the pyridoxine (vitamin B6) biosynthesis enzyme PDX1 in ultraviolet-B radiation responses in plants

Cited by 38 publications

References 37 publications

Does Abiotic Stress Cause Functional B Vitamin Deficiency in Plants?

Does Abiotic Stress Cause Functional B Vitamin Deficiency in Plants?

CIRCADIAN CLOCK-ASSOCIATED 1 regulates ROS homeostasis and oxidative stress responses

The UVR8 UV-B Photoreceptor: Perception, Signaling and Response

Contact Info

Product

Resources

About