“…Pairing of an unconditioned stimulus (US; foot shock) and the conditioning stimulus (CS) leads to conditioned fear when testing occurs later in the same context (context A) (2,13,14). Increasing the intensity of the US produces fear generalization even when testing occurs later in a new context (context B), with different shape, size, texture, and color (14)(15)(16). We validated these findings by testing the effects of a single weak foot shock (0.5 mA, 1 s) and five strong (1.5 mA, 2 s) foot shocks on acquisition of conditioned and generalized fear in mice.…”