The role of the carbohydrate moiety in the structure of the collagen fibril

Replacement of lime with carbohydrases – a successful cleaner process for leather making

“…In order to produce a good substrate for leather making, the carbohydrate moieties should be removed from the dehaired skin matrix. It has been reported that these molecules are present in polysaccharide form and not as individual sugar (Oneson et al, 1960).The fact that liberation of carbohydrate residues from skin could be achieved by the combined action of heat and acid for carbohydrate assay indicates the firm binding of carbohydrate to skin matrix. In order to remove such a firmly bound material, the activity and specificity of enzyme is very crucial.…”

Experimental Lathyrism: Apparent Antithesis of Aging in Connective Tissue

“…Unfortunately the information at this time is far from complete. In the literature covering the subject of collagen fibrillogenesis, one finds a wide variety of evidence and opinion regarding the role of non‐collagenous materials both in the formation and in the stabilization of the fibrous structure (37, 38, 40‐47). The material most often singled out for attention is mucopolysaccharide.…”

Addendum

“…Evidence that particular minor components of collagen are involved in cross-links between side chains has been obtained (carbohydrate, Hormann, 1960;Oneson & Zacharias, 1960; €-amino group of lysine, Levy, Fishman 8r Cabrera, 1960;Betheil & Gallop, 1960;Franzblau, Seifter & Gallop, 1961 -4 beginning has been made by Loewi, Glynn & Dorling (1960) in the chemical identification of ' collastin'.…”