The role of the angular gyrus in the modulation of visuospatial attention by the mental number line

Cattaneo, Zaira; Silvanto, Juha; Pascual‐Leone, Álvaro; Battelli, Lorella

doi:10.1016/j.brs.2008.06.144

Cited by 17 publications

(25 citation statements)

References 38 publications

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“…This finding is consistent with previ- ous results that the right angular gyrus was involved in numerical processing (e.g., Cattaneo et al, 2009;Göbel et al, 2001;Keller and Menon, 2009;Menon et al, 2000). For example, Menon et al (2000) found a greater activation for three-operand arithmetic problems relative to two-operand arithmetic problems at the right angular gyrus as well as the left angular gyrus.…”

Section: Discussionsupporting

confidence: 90%

“…Some studies suggest that the right parietal lobe might be involved in numerical processing (e.g., Cattaneo, Silvanto, Pascual-Leone, & Battelli, 2009;Chochon et al, 1999;R. Cohen Kadosh, K. Cohen Kadosh, Schuhmann, et al, 2007;Göbel, Walsh, & Rushworth, 2001;Keller & Menon, 2009;Menon, Rivera, White, Glover, & Reiss, 2000;Venkatramana, Ansarib, & Chee, 2005).…”

mentioning

confidence: 99%

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Dissociation of subtraction and multiplication in the right parietal cortex: Evidence from intraoperative cortical electrostimulation

Chen

et al. 2011

Neuropsychologia

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a b s t r a c tPrevious research has consistently shown that the left parietal cortex is critical for numerical processing, but the role of the right parietal lobe has been much less clear. This study used the intraoperative cortical electrical stimulation approach to investigate neural dissociation in the right parietal cortex for subtraction and multiplication. Results showed that multiplication (as well as picture naming) was not affected by the cortical electrical stimulation on all the targeted sites of the right parietal cortex as well as those of the right temporal cortex. In contrast, stimulation at three right parietal sites (two sites in the right inferior parietal lobule and one in the right angular gyrus) impaired performance on simple subtraction problems. This study provided the first evidence from an intraoperative cortical electrical stimulation study to show the dissociation of arithmetic operations in the right parietal cortex. This dissociation between subtraction and multiplication suggests that the right parietal cortex plays a more significant role in quantity processing (subtraction) than in verbal processing (multiplication) in numerical processing.

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Section: Discussionsupporting

confidence: 90%

mentioning

confidence: 99%

Dissociation of subtraction and multiplication in the right parietal cortex: Evidence from intraoperative cortical electrostimulation

Chen

et al. 2011

Neuropsychologia

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“…Furthermore, there is little evidence from previous studies that transcallosal excitation spread to the homolog parietal area makes a substantial contribution to the behavioral effects obtained with TMS. Indeed, many studies found a specific deterioration in performance with unilateral TMS over one hemisphere but not over the contralateral homolog area (30)(31)(32). The fact that most previous studies revealed a clear asymmetric sensitivity of the right and left parietal cortex to TMS lesions argues against a significant contribution of transcallosal excitation of the homolog area to the TMS-induced effects.…”

Section: Discussionmentioning

confidence: 99%

Phonological decisions require both the left and right supramarginal gyri

Hartwigsen

Baumgaertner

Price

et al. 2010

Proc. Natl. Acad. Sci. U.S.A.

295

218

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Recent functional imaging studies demonstrated that both the left and right supramarginal gyri (SMG) are activated when healthy right-handed subjects make phonological word decisions. However, lesion studies typically report difficulties with phonological processing after left rather than right hemisphere damage. Here, we used a unique dual-site transcranial magnetic stimulation (TMS) approach to test whether the SMG in the right hemisphere contributes to modality-independent (i.e., auditory and visual) phonological decisions. To test task-specificity, we compared the effect of real or sham TMS during phonological, semantic, and perceptual decisions. To test laterality and anatomical specificity, we compared the effect of TMS over the left, right, or bilateral SMG and angular gyri. The accuracy and reaction times of phonological decisions were selectively disrupted relative to semantic and perceptual decisions when real TMS was applied over the left, right, or bilateral SMG. These effects were not observed for TMS over the angular gyri. A follow-up experiment indicated that the threshold-intensity for inducing a disruptive effect on phonological decisions was identical for unilateral TMS over the right or left SMG. Taken together, these findings provide converging evidence that the right SMG contributes to accurate and efficient phonological decisions in the healthy brain, with no evidence that the left and right SMG can compensate for one another during TMS. Our findings motivate detailed studies of phonological processing in patients with acute or long-term damage of the right SMG.M any previous functional imaging studies have shown that the left and right supramarginal gyri (SMG) are activated when right-handed participants make decisions about the sounds of words (i.e., their phonology) compared with decisions about their meanings (i.e., their semantics) (1-4). However, the functional significance of right SMG activation is unclear because lesion studies have reported phonological difficulties following left rather than right temporo-parietal lesions (5-8). Consequently, anatomical models of phonological processing have included left but not right parietal cortex (9, 10). The present study was designed to address the discrepancy between functional imaging and lesion studies. More specifically, we examined how "online" transcranial magnetic stimulation (i.e., TMS during a task) over the left and right SMG influences phonological word processing in healthy subjects (Fig. 1). We used the neurodisruptive effect of TMS to distinguish between three alternative hypotheses to explain right SMG activation with phonological processing.Hypothesis 1 is that right SMG only contributes to the speed but not the accuracy of phonological decisions. Consequently, right SMG lesions have a subtle effect on phonological processing that might be missed unless reaction times were measured. In this case, we expect a selective effect of right SMG TMS on reaction times in the healthy brain without affecting error rates.Hypothesis 2 i...

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“…Previous studies that have used transcranial magnetic stimulation (TMS) to temporarily disrupt parietal cortex have shown that the right angular gyrus (AG) and supramarginal gyrus (SMG) play a critical role in various aspects of selective attention (Cattaneo et al, 2009;Chambers et al, 2006;Gobel et al, 2001;Hilgetag et al, 2001;Schenkluhn et al, 2008;Zenon et al, 2009). In particular, these parietal regions are important for shifting attention to unisensory stimuli both within and between the senses (Chambers et al, 2007;Chambers et al, 2004a), suggesting that they may also play a role in the perception of stimuli arising simultaneously from multiple sensory modalities.…”

Section: Introductionmentioning

confidence: 99%

“…Here, we use MRI-guided TMS to investigate the unique contributions of two distinct subregions within the inferior parietal lobule, the AG and SMG, in the sound-induced flash illusion. Based on previous studies of the critical role of the AG in regulating selective attention (e.g., Cattaneo et al, 2009;Chambers et al, 2004a;Gobel et al, 2001;Muggleton et al, 2008;Zenon et al, 2009), we predicted that disruption of this area would decrease the influence of attentional control mechanisms on the binding of visual and auditory information, thereby leading to a change in illusory flash perception.…”

Section: Introductionmentioning

confidence: 99%

Parietal disruption alters audiovisual binding in the sound-induced flash illusion

et al. 2012

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Selective attention and multisensory integration are fundamental to perception, but little is known about whether, or under what circumstances, these processes interact to shape conscious awareness. Here, we used transcranial magnetic stimulation (TMS) to investigate the causal role of attention-related brain networks in multisensory integration between visual and auditory stimuli in the sound-induced flash illusion. The flash illusion is a widely studied multisensory phenomenon in which a single flash of light is falsely perceived as multiple flashes in the presence of irrelevant sounds. We investigated the hypothesis that extrastriate regions involved in selective attention, specifically within the right parietal cortex, exert an influence on the multisensory integrative processes that cause the flash illusion. W e found that disruption of the right angular gyrus, but not of the adjacent supramarginal gyrus or of a sensory control site, enhanced participants' veridical perception of the multisensory events, thereby reducing their susceptibility to the illusion. Our findings suggest that the same parietal networks that normally act to enhance perception of attended events also play a role in the binding of auditory and visual stimuli in the sound-induced flash illusion.

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The role of the angular gyrus in the modulation of visuospatial attention by the mental number line

Cited by 17 publications

References 38 publications

Dissociation of subtraction and multiplication in the right parietal cortex: Evidence from intraoperative cortical electrostimulation

Dissociation of subtraction and multiplication in the right parietal cortex: Evidence from intraoperative cortical electrostimulation

Phonological decisions require both the left and right supramarginal gyri

Parietal disruption alters audiovisual binding in the sound-induced flash illusion

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