The Rôle of the Adrenal Cortex in Physiological Processes

Adrenal Involvement in Determining the Time of Onset of Puberty in the Rat1

“…Addisonian patient (121). With the availability of crystalized steroids it was shown that desoxycorticosterone was the most potent cause of retention of sodium and the excretion of potassium (197). Most of the isolated steroids were shown to cause some sodium retention.…”

Studies on the Combined Use of Measurements of Sweat Electrolyte Composition and Rate of Sweating as an Index of Adrenal Cortical Activity 1

“…10 normal subjects (seven male, three female) eating the standard diet during the summer; b) nine normal subjects (five male, four female) eating the standard diet during the winter; c) seven hypoadrenocortical subjects of which -three were male and four female. Collections of sweat were made from the hypoadrenocortical patients during both seasons of the year.…”

“…Effect of varying the dietary intake of sodium chloride and potassium salts. Figure 5 portrays data obtained in experiments involving one normal male (Table I between 10 and 30 gms., 0.6 and 8.6 gms. and 3.5 and 11.5 gms., respectively.…”

The Bioassay of Adrenal Corticoids in the Urine of Patients With Congestive Heart Failure

“…With an increase in adrenal cortical activity sodium retention would be expected, since some of the cortical hormones, especially desoxycorticosterone, act on the renal tubules to promote the reabsorption of sodium from the glomerular filtrate (19,20).…”