The role of the adenylate kinase 5 gene in various diseases and cancer
M. Sarim Siddiqui,
Mehdi H. Shahi,
Javier S. Castresana
Abstract:Adenylate kinases (AKs) are important enzymes involved in cellular energy metabolism. Among AKs, AK5 (adenylate kinase 5), a cytosolic protein, is emerging as a significant contributor to various diseases and cellular processes. This comprehensive review integrates findings from various research groups on AK5 since its discovery, shedding light on its multifaceted roles in nucleotide metabolism, energy regulation, and cellular differentiation. We investigate its implications in a spectrum of diseases, includin… Show more
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